Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | BCR | P11274 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13079694 | 0.86 | NPC1 (0.57) | NPC1TP53MAPK1CASP3RAB9A | |
| SCHEMBL12386386 | 0.86 | NPC1 (0.57) | NPC1TP53MAPK1CASP3RAB9A | |
| SCHEMBL6688965 | 0.86 | NPC1 (0.55) | NPC1TP53MAPK1CASP3RAB9A | |
| SCHEMBL13222288 | 0.85 | MAOB (0.46) | NPC1TP53MAPK1CASP3RAB9A | |
| SCHEMBL6285826 | 0.84 | MAOB (0.59) | NPC1TP53MAPK1CASP3RAB9A | |
| Perchlorate SCHEMBL9177362 | 0.83 | NPC1 (0.47) | NPC1TP53MAPK1CASP3RAB9A | |
| Perchlorate SCHEMBL11044837 | 0.83 | NPC1 (0.51) | NPC1TP53MAPK1CASP3RAB9A | |
| SCHEMBL9175782 | 0.80 | MAOB (0.41) | NPC1TP53MAPK1CASP3RAB9A | |
| SCHEMBL11050461 | 0.80 | ABL1 (0.50) | NPC1TP53MAPK1CASP3RAB9A | |
| SCHEMBL6685513 | 0.80 | ABL1 (0.55) | NPC1TP53MAPK1CASP3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110318689-A1 | LIGHT-SENSITIVE LITHOGRAPHIC PRINTING PLATE MATERIAL | MITSUBISHI PAPER MILLS LIMITED (JP) | 2011-12-29 | — | — | US | disclosed |