Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.46 |
| ▸ | ABCC2 | Q92887 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.46 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14209838 | 0.90 | CYSLTR2 (0.48) | CYSLTR1CYSLTR2PTGER1PTGER4PTGER3 | |
| SCHEMBL30497375 | 0.88 | CYSLTR2 (0.49) | CYSLTR1CYSLTR2PTGER1PTGER4PTGER3 | |
| SCHEMBL201960 | 0.88 | CYSLTR2 (0.49) | CYSLTR1CYSLTR2PTGER1PTGER4PTGER3 | |
| SCHEMBL29517073 | 0.88 | CYSLTR2 (0.49) | CYSLTR1CYSLTR2PTGER1PTGER4PTGER3 | |
| SCHEMBL201961 | 0.88 | CYSLTR2 (0.49) | CYSLTR1CYSLTR2PTGER1PTGER4PTGER3 | |
| SCHEMBL13950635 | 0.86 | CYSLTR2 (0.50) | CYSLTR1CYSLTR2PTGER1PTGER4PTGER3 | |
| SCHEMBL4416755 | 0.85 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL4416752 | 0.85 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL8496429 | 0.85 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2MEN1ABCB11KMT2A | |
| SCHEMBL8496432 | 0.85 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2MEN1ABCB11KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100292251-A1 | MONTELUKAST BENZHYDRYL PIPERAZINE SALTS AND PROCESS FOR PREPARATION THEREOF | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-18 | — | — | US | disclosed |
| US-20100063291-A1 | PROCESS FOR PREPARATION OF SOLID MONTELUKAST | DR. REDDY'S LABORATORIES, INC. (US) | 2010-03-11 | — | — | US | disclosed |
| WO-2008058118-A2 | PREPARATION OF MONTELUKAST AND ITS SALTS | DR. REDDY'S LABORTORIES, LTD. (IN) | 2008-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292251-A1 | MONTELUKAST BENZHYDRYL PIPERAZINE SALTS AND PROCESS FOR PREPARATION THEREOF | CMA1, CYSLTR2, CYSLTR1 | CYSLTR1 3/4885CYSLTR2 2/4885PTGER1 8/4885 |
| US-20100063291-A1 | PROCESS FOR PREPARATION OF SOLID MONTELUKAST | MPST, CMA1, TPMT | CYSLTR1 14/4885CYSLTR2 16/4885PTGER1 263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.