MPST

3-mercaptopyruvate sulfurtransferase · P25325 · MPST on Sugi Atlas →

0 patent compounds predicted against MPST, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to MPST by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Iduronate-2-sulfatase Enzyme Replacement Therapy in Mucopolysaccharidosis II (MPS II) PHASE2/PHASE3COMPLETED
Extension of Study TKT024 Evaluating Long-Term Safety and Clinical Outcomes in MPS II Patients Receiving Idursulfase PHASE2/PHASE3COMPLETED
Extension Study of Idursulfase-IT Along With Elaprase in Children and Adults With Hunter Syndrome and Cognitive Impairment PHASE2/PHASE3ACTIVE_NOT_RECRUITING
Open-Label Study of Efficacy and Safety of Recombinant Human N-acetylgalactosamine 4-sulfatase in Patients With MPS VI PHASE2COMPLETED
Gene Therapy with Modified Autologous Hematopoietic Stem Cells for Patients with Mucopolysaccharidosis Type IIIA PHASE1/PHASE2ACTIVE_NOT_RECRUITING
Evaluation of Losartan on Cardiovascular Disease in Patients With Mucopolysaccharidoses IV A and VI PHASE2UNKNOWN
Safety, Tolerability, Ascending Dose and Dose Frequency Study of rhHNS Via an IDDD in MPS IIIA Patients PHASE1/PHASE2COMPLETED
Vaccine Treatment for Advanced Non-Small Cell Lung Cancer PHASE1/PHASE2COMPLETED
Evaluation of Thiosulfate in End Stage Renal Disease and Kidney Transplantation PHASE1COMPLETED
Study of Recombinant Human N-Acetylgalactosamine 4-Sulfatase in Patients With MPS VI PHASE1COMPLETED
Dietary Effects of Sulfur Amino Acids nanCOMPLETED
Biomarker for Sanfilippo Type A-B-C-D Disease (BioSanfilippo) nanWITHDRAWN
A Natural History Study of Biomarkers and Clinical Outcomes in Mucopolysaccharidosis Type IIIA (MPS IIIA; Sanfilippo Syndrome) nanCOMPLETED
Ophthalmic Manifestations of Patients With Mucopolysaccharidosis nanUNKNOWN
Effect of Sulfur Amino Acid Depletion and Acetaminophen on Plasma Glutatione nanCOMPLETED
Biomarker for Hurler Disease (BioHurler) nanWITHDRAWN
Natural History Study of Patients With MPS IIIA nanCOMPLETED
A Study of Patients With Sanfilippo Syndrome Type A (MPS IIIA) nanCOMPLETED
Chest Wall Deformities in Children - Epidemiological Data nanCOMPLETED
Evaluation of Cardiac Affections in Patients With Mucopolysaccharidosis (MPS) in Assuit University Children Hospital (AUCH) nanUNKNOWN
Rare Kidney Stone Consortium Patient Registry nanRECRUITING
Longitudinal Studies of Brain Structure and Function in MPS Disorders nanCOMPLETED
Functional Pharmacogenomics of Childhood Acute Lymphoblastic Leukemia in Taiwan nanUNKNOWN
The Effect of Enzyme Replacement Therapy in Mucopolysaccharidosis nanCOMPLETED
The Intensively Follow-up Examinations for Asymptomatic MPS I Infants in Taiwan nanUNKNOWN
Establishment of Human Cellular Disease Models for Morquio Disease nanCOMPLETED
The Natural History Study of Patients With Sanfilippo Disease(s) (MPS3) nanUNKNOWN
Sialic Acid Supplementation in N-Acetylneuraminic Acid Synthase (NANS) Deficiency nanCOMPLETED
Core Outcome Set for Head, Neck and Respiratory Disease in Mucopolysaccharidosis II nanCOMPLETED
Post-trial Access Program of Idursulfase-IT Along With Elaprase in Children With Hunter Syndrome nanAVAILABLE

Related proteins — ESM-2 sequence neighbours (a MPST binder may also engage these)

ProteinNameSimilarity
P97532 0.986 P97532 →
TST Thiosulfate sulfurtransferase 0.979 landscape →
P52196 0.968 P52196 →
P24329 0.968 P24329 →
P46635 0.966 P46635 →
P25324 0.966 P25324 →
P00586 0.961 P00586 →
Q99J99 0.951 Q99J99 →
A6NDG6 0.928 A6NDG6 →
Q5I0D5 0.926 Q5I0D5 →
Q9UHB4 0.925 Q9UHB4 →
Q1JPJ0 0.923 Q1JPJ0 →
P60487 0.923 P60487 →
A4FV98 0.922 A4FV98 →
Q2T9S4 0.921 Q2T9S4 →
Q96AZ1 0.920 Q96AZ1 →
Q9H008 0.920 Q9H008 →
Q9D7I5 0.920 Q9D7I5 →
Q8R2H9 0.920 Q8R2H9 →
Q9NTJ4 0.919 Q9NTJ4 →
Q96GD0 0.918 Q96GD0 →
Q5F4B1 0.917 Q5F4B1 →
Q4PS77 0.917 Q4PS77 →
Q8N465 0.917 Q8N465 →
PHOSPHO1 Phosphoethanolamine/phosphocholine phosphatase 0.917 landscape →
Q8IZ69 0.917 Q8IZ69 →
Q5SUV1 0.917 Q5SUV1 →
Q5BJJ5 0.916 Q5BJJ5 →
NT5M 5'(3')-deoxyribonucleotidase, mitochondrial 0.916 landscape →
Q3ZBF9 0.915 Q3ZBF9 →