Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.56 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9346521 | 0.84 | MAP3K5 (0.41) | MAP3K5NUDT1HSD17B10PDPK1GDA | |
| SCHEMBL763254 | 0.81 | MAP3K5 (0.39) | MAP3K5HSD17B10TP53CYP1A2CYP2C19 | |
| SCHEMBL757120 | 0.81 | MAP3K5 (0.41) | MAP3K5NUDT1HSD17B10TP53PDPK1 | |
| SCHEMBL21755893 | 0.81 | MAP3K5 (0.41) | MAP3K5NUDT1HSD17B10CYP1A2POLB | |
| SCHEMBL10410694 | 0.80 | MAP3K5 (0.38) | MAP3K5HSD17B10TP53 | |
| SCHEMBL8826177 | 0.79 | SLC29A1 (0.47) | MAP3K5NUDT1HSD17B10CYP1A2POLB | |
| SCHEMBL129934 | 0.79 | MAP3K5 (0.37) | MAP3K5HSD17B10TP53 | |
| SCHEMBL130807 | 0.79 | MAP3K5 (0.37) | MAP3K5HSD17B10TP53CDK2 | |
| SCHEMBL130532 | 0.79 | MAP3K5 (0.37) | MAP3K5HSD17B10TP53 | |
| SCHEMBL2891515 | 0.78 | MAP3K5 (0.37) | MAP3K5NUDT1HSD17B10TP53PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118931997-A | Method for synthesizing adenosine and/or uridine by three-enzyme cascade catalysis | 上海飞腾医药科技有限公司 | 2024-11-12 | — | — | CN | claimed |
| EP-0679657-B1 | Nucleosides and oligonucleotides containing 2'-ether groups | NOVARTIS AG (CH) | 2003-07-09 | — | — | EP | claimed |
| EP-0741741-B1 | MODIFIED OLIGONUCLEOTIDES | NOVARTIS AG (CH) | 2002-08-28 | — | — | EP | claimed |
| US-6066447-A | INCLUDING NUCLEOSIDE DIMERS WITH MODIFIED BACKBONES; FOR VIRICIDES AND ANTISENSE AGENTS | NOVARTIS CORPORATION (US) | 2000-05-23 | — | — | US | claimed |
| EP-0626387-B1 | Nucleosides and oligonucleotides with 2'-ether groups | NOVARTIS AG (CH) | 1999-03-10 | — | — | EP | claimed |
| WO-1998000434-A1 | MODIFIED OLIGONUCLEOTIDES | NOVARTIS AG (CH) | 1998-01-08 | — | — | WO | claimed |
| US-5700920-A | SYNTHETIC NUCLEOTIDE COMPRISING BICYCLOHEPTANE OR/AND BICYCLOHEXANE RING; VIRICIDES | NOVARTIS CORPORATION (US) | 1997-12-23 | — | — | US | claimed |
| EP-0644196-B1 | TTTr as a protecting group in nucleotide synthesis | CIBA GEIGY AG (CH) | 1997-11-05 | — | — | EP | claimed |
| EP-0799834-A1 | Modified nucleotides | Novartis AG (CH) | 1997-10-08 | — | — | EP | claimed |
| US-5639867-A | TTTr as protective group in nucleotide synthesis | CIBA GEIGY CORPORATION (US) | 1997-06-17 | — | — | US | claimed |
| EP-0679657-A2 | Nucleosides and oligonucleotides containing 2'-ether groups | CIBA-GEIGY AG (CH) | 1995-11-02 | — | — | EP | claimed |
| WO-1995020597-A1 | MODIFIED OLIGONUCLEOTIDES | CIBA-GEIGY AG (CH) | 1995-08-03 | — | — | WO | claimed |
| EP-0644196-A1 | TTTr as a protecting group in nucleotide synthesis | CIBA-GEIGY AG (CH) | 1995-03-22 | — | — | EP | claimed |
| EP-0626387-A1 | Nucleosides and oligonucleotides with 2'-ether groups | CIBA-GEIGY AG (CH) | 1994-11-30 | — | — | EP | claimed |
| EP-0612994-A2 | Matrix for matrix-assisted laser desorption mass spectroscopy | CIBA-GEIGY AG (CH) | 1994-08-31 | — | — | EP | claimed |
| US-5332814-A | Process for the preparation of carbacyclic nucleosides, and intermediates | CIBA-GEIGY CORPORATION (US) | 1994-07-26 | — | — | US | claimed |
| US-5319080-A | Antiviral agents | CIBA-GEIGY CORPORATION (US) | 1994-06-07 | — | — | US | claimed |
| EP-0577558-A2 | Carbocyclic nucleosides having bicyclic rings, oligonucleotides therefrom, process for their preparation, their use and intermediates | CIBA-GEIGY AG (CH) | 1994-01-05 | — | — | EP | claimed |
| EP-0542681-A1 | Process for the preparation of carbocyclic nucleosides and its intermediates | CIBA-GEIGY AG (CH) | 1993-05-19 | — | — | EP | claimed |
| EP-0538194-A1 | Bicyclic nucleosides, oligonucleotides, their method of preparation and intermediates therein | CIBA-GEIGY AG (CH) | 1993-04-21 | — | — | EP | claimed |