Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8350294 | 0.80 | MAPT (0.56) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL7870289 | 0.79 | RAB9A (0.37) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL9570224 | 0.79 | PDE10A (0.50) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL13080931 | 0.78 | MAPT (0.41) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL7863445 | 0.77 | RAB9A (0.45) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL13080129 | 0.76 | GRIN1 (0.40) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL8505541 | 0.76 | RAB9A (0.40) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL8811947 | 0.76 | KMT2A (0.39) | RAB9ASMN1; SMN2NPC1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL7868683 | 0.75 | RAB9A (0.39) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL13050218 | 0.71 | KMT2A (0.33) | NPC1MEN1KMT2AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8343973-B2 | Phenoxymethyl heterocyclic compounds | ENVIVO PHARMACEUTICALS, INC. (US) | 2013-01-01 | — | — | US | disclosed |
| US-20100292238-A1 | Phenoxymethyl Heterocyclic Compounds | FMR LLC | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292238-A1 | Phenoxymethyl Heterocyclic Compounds | PDE3A, PDE2A, PDE5A | MAPT 1299/4885RAB9A 1008/4885SMN1; SMN2 331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.