Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306185 | 0.95 | HPGD (0.42) | HPGDALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL1307673 | 0.89 | HPGD (0.41) | HPGDALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL1306732 | 0.88 | ALDH1A1 (0.45) | HPGDALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL1307651 | 0.88 | HPGD (0.41) | HPGDALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL1307032 | 0.81 | HPGD (0.46) | HPGDALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL3818854 | 0.81 | HPGD (0.46) | HPGDALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL12034908 | 0.81 | HPGD (0.43) | HPGDALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL1307339 | 0.80 | HPGD (0.47) | HPGDALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL12053721 | 0.79 | HPGD (0.42) | HPGDALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL12117301 | 0.79 | HPGD (0.45) | HPGDALDH1A1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053431-B2 | Pharmaceutical use of substituted amides | HIGH POINT PHARMACEUTICALS, LLC (US) | 2011-11-08 | — | — | US | disclosed |