⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1032380 | 0.75 | — | — | |
| SCHEMBL1030415 | 0.75 | — | — | |
| SCHEMBL13833785 | 0.73 | — | — | |
| SCHEMBL1029536 | 0.71 | — | — | |
| SCHEMBL13165168 | 0.71 | TSHR (0.30) | — | |
| SCHEMBL19199017 | 0.69 | ALDH1A1 (0.32) | — | |
| SCHEMBL16316042 | 0.69 | — | — | |
| SCHEMBL436329 | 0.68 | — | — | |
| SCHEMBL1450292 | 0.68 | — | — | |
| SCHEMBL13851910 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132662-A1 | POWDER FORMULATIONS OF POTASSIUM-BINDING ACTIVE AGENTS | RELYPSA, INC. (US) | 2010-11-18 | — | — | WO | disclosed |
| WO-2010022380-A2 | LINEAR POLYOL STABILIZED POLYFLUOROACRYLATE COMPOSITIONS | RELYPSA, INC. (US) | 2010-02-25 | — | — | WO | disclosed |
| WO-2010022381-A1 | TREATING HYPERKALEMIA WITH CROSSLINKED CATION EXCHANGE POLYMERS OF IMPROVED PHYSICAL PROPERTIES | RELYPSA, INC. (US) | 2010-02-25 | — | — | WO | disclosed |
| WO-2010022383-A2 | CROSSLINKED CATION EXCHANGE POLYMERS, COMPOSITIONS AND USE IN TREATING HYPERKALEMIA | RELYPSA, INC. (US) | 2010-02-25 | — | — | WO | disclosed |