Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 4/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | CTSG | P08311 | 2/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.35 |
| ▸ | CMA1 | P23946 | 2/20 | 0.35 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8334313 | 0.81 | KIF11 (0.44) | CSNK1EKIF11ALDH1A1 | |
| SCHEMBL5314905 | 0.80 | CNR2 (0.38) | CSNK1EKIF11CNR2ALDH1A1PRSS1 | |
| SCHEMBL31676108 | 0.80 | HSD17B10 (0.47) | KIF11CNR2 | |
| SCHEMBL31578689 | 0.78 | KIF11 (0.50) | KIF11 | |
| SCHEMBL134594 | 0.74 | HSD17B10 (0.51) | KIF11POLB | |
| SCHEMBL18704762 | 0.73 | KIF11 (0.36) | CSNK1EKIF11CNR2ALDH1A1PRSS1 | |
| SCHEMBL10418792 | 0.73 | CSNK1E (0.40) | CSNK1EKIF11ALDH1A1 | |
| SCHEMBL11411634 | 0.72 | MEN1 (0.45) | CSNK1ECNR2ALDH1A1PRSS1CTSG | |
| SCHEMBL18660141 | 0.72 | CSNK1E (0.44) | CSNK1ECNR2ALDH1A1PRSS1CTSG | |
| SCHEMBL25400196 | 0.72 | KIF11 (0.42) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961263-B2 | Cell-penetrating, guanidinium-rich oligophosphotriesters for drug and probe delivery | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2021-03-30 | — | — | US | disclosed |
| US-20200308200-A1 | CELL-PENETRATING, GUANIDINIUM-RICH OLIGOPHOSPHOTRIESTERS FOR DRUG AND PROBE DELIVERY | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2020-10-01 | — | — | US | disclosed |
| US-10654875-B2 | Cell-penetrating, guanidinium-rich oligophosphotriesters for drug and probe delivery | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-05-19 | — | — | US | disclosed |
| US-20180319825-A1 | CELL-PENETRATING, GUANIDINIUM-RICH OLIGOPHOSPHOTRIESTERS FOR DRUG AND PROBE DELIVERY | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2018-11-08 | — | — | US | disclosed |
| EP-3373977-A1 | CELL-PENETRATING, GUANIDINIUM-RICH OLIGOPHOSPHOTRIESTERS FOR DRUG AND PROBE DELIVERY | The Board of Trustees of the Leland Stanford Junior University (US) | 2018-09-19 | — | — | EP | disclosed |
| WO-2017083637-A1 | CELL-PENETRATING, GUANIDINIUM-RICH OLIGOPHOSPHOTRIESTERS FOR DRUG AND PROBE DELIVERY | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-05-18 | — | — | WO | disclosed |
| US-7829275-B2 | Light addressable electrochemical detection of duplex structures | NORTH CAROLINA STATE UNIVERSITY (US) | 2010-11-09 | — | — | US | disclosed |
| US-20100000881-A1 | Electrochemical detection of nucleic acid hybridization | NORTH CAROLINA STATE UNIVERSITY | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180319825-A1 | CELL-PENETRATING, GUANIDINIUM-RICH OLIGOPHOSPHOTRIESTERS FOR DRUG AND PROBE DELIVERY | SLC29A1, SLC29A2, SLC7A1 | CSNK1E 4846/4885KIF11 909/4885CNR2 3031/4885 |
| US-10961263-B2 | Cell-penetrating, guanidinium-rich oligophosphotriesters for drug and probe delivery | SLC29A1, SLC29A2, SLC7A1 | CSNK1E 4846/4885KIF11 909/4885CNR2 3031/4885 |
| US-20200308200-A1 | CELL-PENETRATING, GUANIDINIUM-RICH OLIGOPHOSPHOTRIESTERS FOR DRUG AND PROBE DELIVERY | SLC29A1, SLC29A2, SLC7A1 | CSNK1E 4846/4885KIF11 909/4885CNR2 3031/4885 |
| US-10654875-B2 | Cell-penetrating, guanidinium-rich oligophosphotriesters for drug and probe delivery | SLC29A1, SLC29A2, SLC7A1 | CSNK1E 4846/4885KIF11 909/4885CNR2 3031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.