Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1426765 | 0.86 | PDK1 (0.33) | SMN1; SMN2 | |
| SCHEMBL19711802 | 0.86 | PDK1 (0.33) | SMN1; SMN2 | |
| SCHEMBL16832072 | 0.86 | PDK1 (0.33) | SMN1; SMN2 | |
| SCHEMBL16832561 | 0.86 | PDK1 (0.33) | SMN1; SMN2 | |
| SCHEMBL31439446 | 0.83 | EPHX1 (0.37) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL13865782 | 0.82 | CYP2A6 (0.33) | SMN1; SMN2 | |
| SCHEMBL16846762 | 0.82 | CYP2A6 (0.33) | SMN1; SMN2 | |
| SCHEMBL1426633 | 0.78 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL16846761 | 0.77 | PDK1 (0.30) | — | |
| SCHEMBL22960991 | 0.77 | EPHX1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074093-B1 | PROCESS FOR PREPARING MATRIX METALLOPROTEINASE INHIBITORS AND CHIRAL AUXILIARY THEREFOR | RANBAXY LAB LTD (IN) | 2012-10-10 | — | — | EP | disclosed |