SCHEMBL13085501

SCHEMBL13085501

CNC(=O)c1cc(I)cc(C)c1NC(=O)c1cc(Cn2nnnc2C(F)(F)F)nn1-c1ncccc1Br

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ NTRK1 P04629 1/20 0.31
▸ SLC2A1 P11166 1/20 0.30
▸ SLC2A2 P11168 1/20 0.30
▸ SLC2A3 P11169 1/20 0.30
▸ SLC2A4 P14672 1/20 0.30
▸ PDE10A Q9Y233 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13085553 0.93 — —
SCHEMBL13085351 0.93 CHIA (0.30) —
SCHEMBL13085608 0.93 SLC2A1 (0.32) SLC2A1SLC2A2SLC2A3SLC2A4
SCHEMBL13085500 0.93 PDE4A (0.33) —
SCHEMBL13085505 0.92 MAPK13 (0.36) NTRK1PDE10A
SCHEMBL13085417 0.92 NTRK1 (0.32) NTRK1PDE10A
SCHEMBL11928601 0.92 DHODH (0.34) NTRK1SLC2A1SLC2A2SLC2A3SLC2A4
SCHEMBL13085333 0.91 MAPK14 (0.38) —
SCHEMBL13085305 0.90 SLC2A1 (0.36) NTRK1SLC2A1SLC2A2SLC2A3SLC2A4
SCHEMBL13085458 0.87 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 — — US disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 — — US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 — — US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 NTRK1 2506/4885SLC2A1 2324/4885SLC2A2 2169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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