SCHEMBL13085538

SCHEMBL13085538

Cc1cc(Cl)cc(C(=O)NCC#N)c1NC(=O)c1cc(Cn2nnnc2C(F)(F)F)nn1-c1ncccc1Br

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 3/20 0.32
SLC2A3 P11169 3/20 0.32
SLC2A4 P14672 3/20 0.32
SLC2A2 P11168 2/20 0.32
NTRK1 P04629 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13085499 0.93 GRIN1 (0.31) NTRK1
SCHEMBL13085417 0.91 NTRK1 (0.32) NTRK1
SCHEMBL13085535 0.90 NTRK1 (0.31) NTRK1
SCHEMBL13085483 0.90 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2NTRK1
SCHEMBL13085485 0.90 PDE4A (0.33) NTRK1
SCHEMBL13085540 0.88 MAPK14 (0.37)
SCHEMBL13085192 0.88 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL13085382 0.88 MAPK13 (0.33) SLC2A1SLC2A3SLC2A4SLC2A2NTRK1
SCHEMBL13085396 0.88 SLC2A1 (0.31) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL13085411 0.87 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 SLC2A1 2324/4885SLC2A3 2023/4885SLC2A4 2344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.