Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 5/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | MELK | Q14680 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118497 | 0.92 | CCKBR (0.47) | CCKBRMCHR1MAPK8LMNAMEN1 | |
| SCHEMBL2118500 | 0.92 | CCKBR (0.47) | CCKBRMCHR1MAPK8LMNAMEN1 | |
| SCHEMBL2120515 | 0.88 | CCKBR (0.50) | CCKBRLMNAMEN1ALBKMT2A | |
| SCHEMBL2117635 | 0.82 | CCKBR (0.47) | CCKBRMAPK8LMNAMEN1ALB | |
| SCHEMBL2117626 | 0.81 | CCKBR (0.51) | CCKBRLMNAMEN1ALBKMT2A | |
| SCHEMBL2119687 | 0.80 | CCKBR (0.49) | CCKBRLMNAMEN1ALBKMT2A | |
| SCHEMBL2118545 | 0.79 | CCKBR (0.49) | CCKBRLMNAMEN1ALBKMT2A | |
| SCHEMBL2119913 | 0.79 | CNR2 (0.50) | CCKBR | |
| SCHEMBL13060992 | 0.79 | CCKBR (0.50) | CCKBRLMNAMEN1ALBKMT2A | |
| SCHEMBL13086547 | 0.79 | CHRM1 (0.40) | CCKBRMCHR1MAPK8LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010121164-A2 | 1,4-BENZODIAZEPINONE COMPOUNDS AND THEIR USE IN TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2010-10-21 | — | — | WO | disclosed |