Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | XIAP | P98170 | 1/20 | 0.51 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 11/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15986869 | 0.87 | XIAP (0.64) | RAB9AMAPTXIAPBIRC2KDM4E | |
| SCHEMBL839860 | 0.85 | RAB9A (0.66) | RAB9AMAPTXIAPBIRC2KDM4E | |
| SCHEMBL9891790 | 0.83 | RAB9A (0.68) | RAB9AMAPTXIAPBIRC2KDM4E | |
| SCHEMBL839347 | 0.83 | RAB9A (0.62) | RAB9AMAPTXIAPBIRC2KDM4E | |
| SCHEMBL839227 | 0.83 | RAB9A (0.62) | RAB9AMAPTXIAPBIRC2KDM4E | |
| SCHEMBL839228 | 0.83 | RAB9A (0.62) | RAB9AMAPTXIAPBIRC2KDM4E | |
| SCHEMBL21401471 | 0.81 | RAB9A (0.64) | RAB9AMAPTXIAPBIRC2KDM4E | |
| SCHEMBL17409810 | 0.78 | RAB9A (0.60) | RAB9AMAPTXIAPBIRC2KDM4E | |
| SCHEMBL5034164 | 0.76 | RAB9A (0.72) | RAB9AMAPTKDM4EALDH1A1NPC1 | |
| SCHEMBL7876929 | 0.76 | POLB (0.63) | RAB9AALDH1A1NPC1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010121164-A2 | 1,4-BENZODIAZEPINONE COMPOUNDS AND THEIR USE IN TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2010-10-21 | — | — | WO | disclosed |