Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13085764 | 0.87 | PTGS2 (0.38) | PTGS2GAAMAPTKDM4EHSD17B10 | |
| SCHEMBL13086406 | 0.85 | KDM4E (0.33) | PTGS2KDM4EHSD17B10MEN1HPGD | |
| SCHEMBL13237202 | 0.81 | PTGS2 (0.40) | PTGS2MAPTKDM4EHSD17B10MEN1 | |
| SCHEMBL13086591 | 0.80 | PTGS2 (0.41) | PTGS2GAAMAPTKDM4EHSD17B10 | |
| SCHEMBL13086303 | 0.80 | PTGS2 (0.39) | PTGS2GAAMAPTKDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL2821073 | 0.77 | PTGS2 (0.55) | PTGS2GAAMAPTKDM4EHSD17B10 | |
| SCHEMBL13236593 | 0.77 | KDM4E (0.41) | PTGS2MAPTKDM4EHSD17B10MEN1 | |
| SCHEMBL13237206 | 0.76 | PTGS2 (0.43) | PTGS2MAPTKDM4EHSD17B10MEN1 | |
| SCHEMBL13086283 | 0.75 | PTGS2 (0.40) | PTGS2GAAMAPTKDM4EHSD17B10 | |
| SCHEMBL13236765 | 0.75 | PTGS2 (0.39) | PTGS2KDM4EHSD17B10MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118968-A1 | NO-DONOR ASPIRIN DERIVATIVES | NICOX S.A. (FR) | 2010-10-21 | — | — | WO | disclosed |