Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.37 |
| ▸ | F2 | P00734 | 8/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10049253 | 1.00 | ACE (0.37) | ACEF2F10CASP3CASP1 | |
| SCHEMBL8277312 | 1.00 | ACE (0.37) | ACEF2F10CASP3CASP1 | |
| SCHEMBL10131995 | 1.00 | ACE (0.37) | ACEF2F10CASP3CASP1 | |
| SCHEMBL12253679 | 1.00 | ACE (0.37) | ACEF2F10CASP3CASP1 | |
| SCHEMBL10132024 | 1.00 | ACE (0.37) | ACEF2F10CASP3CASP1 | |
| SCHEMBL10161363 | 1.00 | ACE (0.37) | ACEF2F10CASP3CASP1 | |
| SCHEMBL13086471 | 1.00 | ACE (0.37) | ACEF2F10CASP3CASP1 | |
| SCHEMBL12581451 | 1.00 | ACE (0.37) | ACEF2F10CASP3CASP1 | |
| SCHEMBL12766048 | 1.00 | ACE (0.37) | ACEF2F10CASP3CASP1 | |
| SCHEMBL13815127 | 0.92 | ACE (0.45) | ACEF2F10CASP3CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010120476-A2 | N-TERMINUS CONFORMATIONALLY CONSTRAINED GLP-1 RECEPTOR AGONIST COMPOUNDS | AMYLIN PHARMACEUTICALS, INC. (US) | 2010-10-21 | — | — | WO | disclosed |