SCHEMBL10132024

SCHEMBL10132024

CN[C@@H]1CC[C@H]2SC[C@@H](C(C)=O)N2C1=O

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ACE P12821 4/20 0.37
F2 P00734 8/20 0.37
F10 P00742 2/20 0.37
CASP3 P42574 2/20 0.36
CASP1 P29466 1/20 0.35
XIAP P98170 1/20 0.34
PLG P00747 1/20 0.34
PRSS1 P07477 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10049253 1.00 ACE (0.37) ACEF2F10CASP3CASP1
SCHEMBL8277312 1.00 ACE (0.37) ACEF2F10CASP3CASP1
SCHEMBL10131995 1.00 ACE (0.37) ACEF2F10CASP3CASP1
SCHEMBL12253679 1.00 ACE (0.37) ACEF2F10CASP3CASP1
SCHEMBL10161363 1.00 ACE (0.37) ACEF2F10CASP3CASP1
SCHEMBL13086471 1.00 ACE (0.37) ACEF2F10CASP3CASP1
SCHEMBL12581451 1.00 ACE (0.37) ACEF2F10CASP3CASP1
SCHEMBL13086707 1.00 ACE (0.37) ACEF2F10CASP3CASP1
SCHEMBL12766048 1.00 ACE (0.37) ACEF2F10CASP3CASP1
SCHEMBL13815127 0.92 ACE (0.45) ACEF2F10CASP3CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101186-B2 Peptides that block the binding of IgG to FcRn SYNTONIX PHARMACEUTICALS, INC. (US) 2012-01-24 US disclosed
US-8101186-B2 Peptides that block the binding of IgG to FcRn SYNTONIX PHARMACEUTICALS, INC. (US) 2012-01-24 US disclosed
US-20070254831-A1 PEPTIDES THAT BLOCK THE BINDING OF IgG to FcRn BIOGEN HEMOPHILIA INC. 2007-11-01 US disclosed
US-20070254831-A1 PEPTIDES THAT BLOCK THE BINDING OF IgG to FcRn BIOGEN HEMOPHILIA INC. 2007-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070254831-A1 PEPTIDES THAT BLOCK THE BINDING OF IgG to FcRn FCGRT, FCGR3B, FCGR1A ACE 1806/4885F2 242/4885F10 148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.