⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131722 | 0.90 | SLC1A3 (0.32) | — | |
| SCHEMBL12056418 | 0.90 | PRMT5 (0.34) | — | |
| SCHEMBL12687460 | 0.89 | SPHK2 (0.36) | — | |
| SCHEMBL8977001 | 0.89 | — | — | |
| SCHEMBL12687468 | 0.89 | SPHK2 (0.36) | — | |
| SCHEMBL10228451 | 0.88 | PRMT5 (0.36) | — | |
| SCHEMBL15383223 | 0.85 | TSHR (0.31) | — | |
| SCHEMBL10307716 | 0.84 | TDP1 (0.40) | — | |
| SCHEMBL19795477 | 0.84 | SCN9A (0.32) | — | |
| SCHEMBL10690215 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820864-B2 | Aqueous polyglycidol synthesis with ultra-low branching | VANDERBILT UNIVERSITY (US) | 2023-11-21 | — | — | US | disclosed |
| US-11739087-B2 | Inhibiting (α-v)(β-6) integrin | MORPHIC THERAPEUTIC, INC. (US) | 2023-08-29 | — | — | US | disclosed |
| US-20180134843-A1 | AQUEOUS POLYGLYCIDOL SYNTHESIS WITH ULTRA-LOW BRANCHING | VANDERBILT UNIVERSITY | 2018-05-17 | — | — | US | disclosed |
| US-20180125983-A1 | Linear Polyester and Semi-Linear Glycidol Polymer Systems: Formulation and Synthesis of Novel Monomers and Macromolecular Structures | UNIV VANDERBILT (US) | 2018-05-10 | — | — | US | disclosed |
| US-20170349576-A1 | HETEROARYL SUBSTITUTED PYRIDINES AND METHODS OF USE | ABBVIE S.Á.R.L. (LU) | 2017-12-07 | — | — | US | disclosed |
| US-9757463-B2 | Linear polyester and semi-linear glycidol polymer systems: formulation and synthesis of novel monomers and macromolecular structures | VANDERBILT UNIVERSITY (US) | 2017-09-12 | — | — | US | disclosed |
| US-9745419-B2 | Aqueous polyglycidol synthesis with ultra-low branching | VANDERBILT UNIVERSITY (US) | 2017-08-29 | — | — | US | disclosed |
| US-20160206743-A1 | Linear Polyester and Semi-Linear Glycidol Polymer Systems: Formulation and Synthesis of Novel Monomers and Macromolecular Structures | VANDERBILT UNIVERSITY | 2016-07-21 | — | — | US | disclosed |
| US-9161983-B2 | Linear polyester and semi-linear glycidol polymer systems: formulation and synthesis of novel monomers and macromolecular structures | VANDERBILT UNIVERSITY (US) | 2015-10-20 | — | — | US | disclosed |
| US-20150210805-A1 | AQUEOUS POLYGLYCIDOL SYNTHESIS WITH ULTRA-LOW BRANCHING | VANDERBILT UNIVERSITY | 2015-07-30 | — | — | US | disclosed |
| EP-1982986-B1 | PYRROLOPYRIDAZINONE COMPOUND AS PDE4 INHIBITOR | UBE INDUSTRIES (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-8084472-B2 | Fused pyrrolocarbazoles | CEPHALON, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-20110236348-A1 | MODULATORS OF TOLL-LIKE RECEPTOR 7 | GILEAD SCIENCES, INC. (US) | 2011-09-29 | — | — | US | disclosed |
| US-20110136765-A1 | Pyrrolo[2,3-D]Pyrimidine Compounds | PFIZER INC. (US) | 2011-06-09 | — | — | US | disclosed |
| US-20090186888-A1 | NOVEL FUSED PYRROLOCARBAZOLES | CEPHALON, INC. (US) | 2009-07-23 | — | — | US | disclosed |
| US-7514440-B2 | Fused pyrrolocarbazoles | CEPHALON, INC. (US) | 2009-04-07 | — | — | US | disclosed |
| US-20090036453-A1 | Pyrrolopyridazinone Compound | UBE INDUSTRIES, LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1982986-A1 | PYRROLOPYRIDAZINONE COMPOUND | Ube Industries, Ltd. (JP) | 2008-10-22 | — | — | EP | disclosed |
| US-20070203135-A1 | Novel Fused Pyrrolocarbazoles | CEPHALON, INC. (US) | 2007-08-30 | — | — | US | disclosed |
| US-7241779-B2 | Fused pyrrolocarbazoles | CEPHALON, INC. (US) | 2007-07-10 | — | — | US | disclosed |