Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 2/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12327980 | 0.82 | SSTR3 (0.33) | — | |
| SCHEMBL13087621 | 0.81 | — | — | |
| SCHEMBL17253532 | 0.79 | — | — | |
| SCHEMBL19701044 | 0.79 | — | — | |
| SCHEMBL19578473 | 0.79 | MAPK13 (0.37) | CDC7CCNE1CDK2ROCK1DBF4 | |
| SCHEMBL19388257 | 0.79 | MAPK13 (0.37) | CDC7CCNE1CDK2ROCK1DBF4 | |
| SCHEMBL15457675 | 0.79 | MAPK13 (0.37) | CDC7CCNE1CDK2ROCK1DBF4 | |
| SCHEMBL13221451 | 0.79 | SSTR3 (0.34) | — | |
| SCHEMBL10202377 | 0.79 | SSTR3 (0.34) | — | |
| SCHEMBL17948121 | 0.79 | PYGL (0.33) | CDC7CCNE1CDK2ROCK1DBF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414350-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2014-11-12 | — | — | EP | disclosed |
| WO-2010117635-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-10-14 | — | — | WO | disclosed |