SCHEMBL13087775

SCHEMBL13087775

C1=Cc2c(oc3ccc(-c4cccc(-c5ccc6c(c5)c5ccccc5n6-c5ccccc5)c4)cc23)CC1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 4/20 0.39
PLA2G4A P47712 4/20 0.39
PLA2G10 O15496 1/20 0.39
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PRKDC P78527 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25766597 0.97 KDM4E (0.37) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL21993183 0.94 PLA2G2A (0.38) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL19054200 0.93 PLA2G2A (0.38) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL12175740 0.92 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL13980926 0.91 PLA2G2A (0.32) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL22487614 0.91 PLA2G2A (0.37) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL16500792 0.89 PLA2G2A (0.35) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL12175598 0.89 PLA2G2A (0.33) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL9892611 0.88 PLA2G2A (0.35) PLA2G2APLA2G4APLA2G10PRKDC
SCHEMBL25663203 0.88 ATM (0.38) PLA2G2APLA2G4AKDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100267180-A1 METHOD FOR MANUFACTURING ORGANIC ELECTRONIC ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2010-10-21 US disclosed