SCHEMBL13088660

SCHEMBL13088660

COc1ccc(Nc2ccc3c(O)c(N=Nc4cc(C)c(N=Nc5ccc(N=Nc6ccc(SOOO)cc6)cc5)cc4C)c(SOOO)cc3c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ PRMT1 Q99873 2/20 0.42
▸ CARM1 Q86X55 1/20 0.42
▸ ENPP2 Q13822 6/20 0.40
▸ MAPT P10636 3/20 0.35
▸ KDM4E B2RXH2 2/20 0.35
▸ RAB9A P51151 3/20 0.34
▸ L3MBTL1 Q9Y468 3/20 0.34
▸ NPC1 O15118 2/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ PHLPP2 Q6ZVD8 1/20 0.34
▸ BRD4 O60885 1/20 0.34
▸ PTPN11 Q06124 1/20 0.32
▸ LMNA P02545 2/20 0.32
▸ MEN1 O00255 3/20 0.31
▸ KMT2A Q03164 3/20 0.31
▸ CD40 P25942 1/20 0.31
▸ CD40LG P29965 1/20 0.31
▸ POLB P06746 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13088662 0.96 ENPP2 (0.46) PRMT1CARM1ENPP2MAPTKDM4E
SCHEMBL13088664 0.96 ENPP2 (0.46) PRMT1CARM1ENPP2MAPTKDM4E
SCHEMBL13088655 0.94 PRMT1 (0.46) PRMT1CARM1ENPP2MAPTKDM4E
SCHEMBL13088659 0.92 ENPP2 (0.39) PRMT1CARM1ENPP2RAB9AL3MBTL1
SCHEMBL13088681 0.90 ENPP2 (0.46) PRMT1CARM1ENPP2PHLPP2BRD4
SCHEMBL13088677 0.90 ENPP2 (0.40) PRMT1CARM1ENPP2MAPTKDM4E
SCHEMBL13860911 0.90 ENPP2 (0.53) PRMT1CARM1ENPP2MAPTMAPK1
SCHEMBL13088703 0.90 ENPP2 (0.53) PRMT1CARM1ENPP2MAPTMAPK1
SCHEMBL12568525 0.90 ENPP2 (0.53) PRMT1CARM1ENPP2MAPTMAPK1
SCHEMBL13088667 0.90 ENPP2 (0.46) PRMT1CARM1ENPP2MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100257678-A1 Azo compound and dye polarizing film containing the same POLATECHNO CO., LTD. (JP) 2010-10-14 — — US disclosed
Send feedback