SCHEMBL130890

SCHEMBL130890

CCCCCCCCCCCCCCCC(=O)OC(C)=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.59
LMNA P02545 2/20 0.55
PAM P19021 2/20 0.53
CES2 O00748 3/20 0.52
CES1 P23141 3/20 0.52
MAPT P10636 1/20 0.52
MAPK1 P28482 1/20 0.52
PPARG P37231 5/20 0.50
PPARD Q03181 5/20 0.50
PPARA Q07869 5/20 0.50
HDAC11 Q96DB2 4/20 0.50
TSHR P16473 3/20 0.50
GPR84 Q9NQS5 3/20 0.50
ALDH1A1 P00352 2/20 0.50
TLR2 O60603 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
FABP4 P15090 2/20 0.50
PTPN1 P18031 2/20 0.50
SLC22A6 Q4U2R8 1/20 0.50
SLC22A8 Q8TCC7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50589 1.00 DGKA (0.59) DGKALMNAPAMCES2CES1
SCHEMBL627978 1.00 DGKA (0.59) DGKALMNAPAMCES2CES1
SCHEMBL119874 1.00 DGKA (0.59) DGKALMNAPAMCES2CES1
SCHEMBL17222526 1.00 DGKA (0.59) DGKALMNAPAMCES2CES1
SCHEMBL2235744 1.00 DGKA (0.59) DGKALMNAPAMCES2CES1
SCHEMBL22126637 1.00 DGKA (0.59) DGKALMNAPAMCES2CES1
SCHEMBL60795 1.00 DGKA (0.59) DGKALMNAPAMCES2CES1
SCHEMBL1698285 1.00 DGKA (0.59) DGKALMNAPAMCES2CES1
SCHEMBL4631670 1.00 DGKA (0.59) DGKALMNAPAMCES2CES1
SCHEMBL3219935 1.00 DGKA (0.59) DGKALMNAPAMCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3061 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116710123-A Cytokine release and inhibition of cytokine storm 萨恩帕斯药物有限公司 2023-09-05 CN claimed
EP-4188398-A1 SUPPRESSION OF CYTOKINE RELEASE AND CYTOKINE STORM Signpath Pharma, Inc. (US) 2023-06-07 EP claimed
EP-3151837-B1 PROTECTIVE EFFECT OF DMPC, DMPG, DMPC/DMPG, EGPG, LYSOPG AND LYSOPC AGAINST DRUGS THAT CAUSE CHANNELOPATHIES SIGNPATH PHARMA INC (US) 2023-03-15 EP claimed
EP-3082768-B1 LIPOSOMAL MITIGATION OF DRUG-INDUCED INHIBITION OF THE CARDIAC IKR CHANNEL SIGNPATH PHARMA INC (US) 2023-02-22 EP claimed
US-20220401558-A1 NANOTUBE TRANS-MEMBRANE CHANNELS MIMICKING BIOLOGICAL PORINS U.S. DEPARTMENT OF ENERGY 2022-12-22 US claimed
US-11439708-B2 Nanotube trans-membrane channels mimicking biological porins LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) 2022-09-13 US claimed
CN-114796030-A Skin-refreshing essence and preparation method thereof 安婕妤化妆品科技股份有限公司 2022-07-29 CN claimed
US-20220054389-A1 BOTULINUM NANOEMULSIONS UNIVERSITY OF MASSACHUSETTS LOWELL (US) 2022-02-24 US claimed
WO-2022026170-A1 SUPPRESSION OF CYTOKINE RELEASE AND CYTOKINE STORM SIGNPATH PHARMA, INC. (US) 2022-02-03 WO claimed
CN-113633614-A Efficient antibacterial natural tea tree essential oil nanoemulsion preparation for treating intractable dental ulcer and preparation method and application thereof 中国人民解放军陆军军医大学 2021-11-12 CN claimed
US-6726919-B2 FOR INDUCING OR MAINTAINING ANESTHESIA OR SEDATION IN A PATIENT RTP PHARMA, INC. 2004-04-27 US claimed
WO-2002032396-A9 LIPID-PROTEIN-SUGAR PARTICLES FOR DELIVERY OF NUCLEIC ACIDS MASSACHUSETTS INST TECHNOLOGY (US) 2003-07-17 WO claimed
EP-1292282-A2 IMPROVED INJECTABLE DISPERSIONS OF PROPOFOL RTP Pharma Inc. (CA) 2003-03-19 EP claimed
US-20020150621-A1 Lipid-protein-sugar particles for drug delivery MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2002-10-17 US claimed
US-20020150626-A1 Lipid-protein-sugar particles for delivery of nucleic acids MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2002-10-17 US claimed
WO-2002032398-A2 LIPID-PROTEIN-SUGAR PARTICLES FOR DRUG DELIVERY MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2002-04-25 WO claimed
WO-2002032396-A2 LIPID-PROTEIN-SUGAR PARTICLES FOR DELIVERY OF NUCLEIC ACIDS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2002-04-25 WO claimed
US-20020022667-A1 Injectable dispersions of propofol ASTORA WOMEN'S HEALTH HOLDINGS, LLC 2002-02-21 US claimed
WO-2001097779-A2 IMPROVED INJECTABLE DISPERSIONS OF PROPOFOL RTP PHARMA INC. (CA) 2001-12-27 WO claimed
US-4058122-A Osmotic system with laminated wall formed of different materials ALZA CORPORATION (US) 1977-11-15 US claimed