Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 15/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 14/20 | 0.45 |
| ▸ | DRD2 | P14416 | 12/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2818179 | 0.81 | DRD3 (0.68) | DRD3KCNH2DRD2CYP1A2 | |
| Hydrochloric Acid SCHEMBL2845359 | 0.81 | DRD3 (0.67) | DRD3KCNH2DRD2CYP1A2 | |
| SCHEMBL13606600 | 0.70 | DRD3 (0.58) | DRD3KCNH2DRD2CYP1A2 | |
| SCHEMBL2818562 | 0.67 | DRD3 (0.54) | DRD3KCNH2DRD2CYP1A2 | |
| SCHEMBL2818705 | 0.67 | DRD3 (0.64) | DRD3KCNH2DRD2CYP1A2 | |
| SCHEMBL29864627 | 0.66 | PTGS2 (0.48) | GRIN2BGRIN2ACYP1A2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2844555 | 0.66 | DRD3 (0.63) | DRD3KCNH2DRD2CYP1A2 | |
| SCHEMBL2819960 | 0.66 | DRD3 (0.67) | DRD3KCNH2DRD2CYP1A2 | |
| SCHEMBL2821345 | 0.62 | DRD3 (0.59) | DRD3KCNH2DRD2CYP1A2 | |
| SCHEMBL2819404 | 0.62 | DRD3 (0.59) | DRD3KCNH2DRD2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891057-B1 | AZABICYCLO[3.1.0]HEXANE DERIVAIVES AS DOPAMIN D3 RECEPTOR MODULATORS | GLAXO GROUP LTD (GB) | 2010-10-27 | — | — | EP | disclosed |