SCHEMBL13089924

SCHEMBL13089924

Cc1cccc(N(c2ccc3ccccc3c2)c2cc3cccc4c(N(c5cccc(C)c5)c5ccc6ccccc6c5)cc5cccc2c5c34)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.42
TDP1 Q9NUW8 2/20 0.42
NR1I2 O75469 1/20 0.42
LMNA P02545 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPT P10636 1/20 0.42
CYP2C9 P11712 1/20 0.42
MAPK1 P28482 1/20 0.42
CYP2C19 P33261 1/20 0.42
HTR2B P41595 1/20 0.42
CYP51A1 Q16850 1/20 0.42
CYP2A6 P11509 2/20 0.41
SIGMAR1 Q99720 4/20 0.39
L3MBTL1 Q9Y468 2/20 0.37
HTT P42858 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
ERBB2 P04626 1/20 0.36
FYN P06241 1/20 0.36
MAOA P21397 1/20 0.36
ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27365572 0.89 CYP1A2 (0.43) CYP1A2TDP1CYP3A4CYP2A6L3MBTL1
SCHEMBL13333766 0.89 CYP1A2 (0.42) CYP1A2TDP1NR1I2LMNACYP3A4
SCHEMBL13320938 0.88 CYP1A2 (0.40) CYP1A2TDP1LMNACYP3A4MAPT
SCHEMBL22253650 0.87 CYP1A2 (0.40) CYP1A2TDP1NR1I2LMNACYP3A4
SCHEMBL12377912 0.86 CYP1A2 (0.40) CYP1A2TDP1NR1I2LMNACYP3A4
SCHEMBL19566266 0.86 CYP1A2 (0.41) CYP1A2TDP1NR1I2LMNACYP3A4
SCHEMBL17952139 0.85 CYP1A2 (0.44) CYP1A2TDP1NR1I2LMNACYP3A4
SCHEMBL21939990 0.85 SIGMAR1 (0.40) CYP1A2TDP1NR1I2LMNACYP3A4
SCHEMBL13320944 0.84 CYP1A2 (0.42) CYP1A2TDP1CYP3A4MAPTCYP2C9
SCHEMBL30670629 0.83 CYP2A6 (0.54) CYP1A2TDP1NR1I2LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100259163-A1 POLYMER COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-10-14 US disclosed
US-20100259163-A1 POLYMER COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-10-14 US disclosed