Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29940658 | 0.84 | MAPT (0.47) | MAPTTP53TSHRALDH1A1HPGD | |
| SCHEMBL7867200 | 0.79 | CYP3A4 (0.61) | MAPTTP53TSHRALDH1A1HPGD | |
| SCHEMBL30715126 | 0.78 | MAPT (0.43) | MAPTTP53TSHRALDH1A1HPGD | |
| SCHEMBL30074142 | 0.72 | POLQ (0.58) | MAPTTP53ALDH1A1HPGDKDM4E | |
| SCHEMBL3871929 | 0.72 | POLQ (0.58) | MAPTTP53ALDH1A1HPGDKDM4E | |
| SCHEMBL18749573 | 0.72 | MRGPRX4 (0.44) | MAPTTSHRALDH1A1HPGDKDM4E | |
| SCHEMBL10348155 | 0.71 | ALDH1A1 (0.42) | MAPTTP53ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL20278053 | 0.71 | SMN1; SMN2 (0.45) | MAPTTP53TSHRALDH1A1HPGD | |
| SCHEMBL11876798 | 0.71 | MAPT (0.36) | MAPTTP53TSHRALDH1A1HPGD | |
| SCHEMBL8785163 | 0.70 | TDP1 (0.40) | MAPTTP53TSHRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010123139-A1 | ARYLCARBOXAMIDE DERIVATIVE HAVING SULFAMOYL GROUP | 持田製薬株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |