Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.55 |
| ▸ | CHKA | P35790 | 7/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | LPL | P06858 | 2/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12530002 | 0.91 | ENPP2 (0.46) | ENPP2CHKAMGLLLPLLIPG | |
| SCHEMBL19696374 | 0.87 | CHKA (0.46) | ENPP2CHKAMGLLBCHEACHE | |
| SCHEMBL12530089 | 0.86 | ENPP2 (0.42) | ENPP2CHKAMGLLLPLLIPG | |
| SCHEMBL12249821 | 0.85 | ENPP2 (0.41) | ENPP2CHKAMGLLLPLLIPG | |
| SCHEMBL2737184 | 0.81 | KDM4E (0.42) | ENPP2CHKAMGLLBCHEACHE | |
| SCHEMBL24044011 | 0.74 | CA1 (0.44) | CHKAMGLLBCHEACHEKDM4E | |
| SCHEMBL12530382 | 0.74 | KDM4E (0.40) | CHKAMGLLBCHEACHEKDM4E | |
| SCHEMBL10137237 | 0.73 | CHKA (0.36) | ENPP2CHKAKDM4EALDH1A1RAB9A | |
| SCHEMBL5872608 | 0.73 | ENPP2 (0.72) | ENPP2MGLLLPLLIPGKDM4E | |
| SCHEMBL19661291 | 0.73 | BCHE (0.56) | CHKABCHEACHEKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8838195-B2 | Optical systems and methods for ratiometric measurement of blood glucose concentration | MEDTRONIC MINIMED, INC. (US) | 2014-09-16 | — | — | US | disclosed |
| US-8738107-B2 | Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement | MEDTRONIC MINIMED, INC. (US) | 2014-05-27 | — | — | US | disclosed |
| US-8498682-B2 | Optical determination of pH and glucose | GLUMETRICS, INC. (US) | 2013-07-30 | — | — | US | disclosed |
| US-20100274110-A1 | OPTICAL DETERMINATION OF PH AND GLUCOSE | GluMetrics, Inc (US) | 2010-10-28 | — | — | US | disclosed |
| US-7751863-B2 | Optical determination of ph and glucose | GLUMETRICS, INC. (US) | 2010-07-06 | — | — | US | disclosed |
| US-20090018418-A1 | EQUILIBRIUM NON-CONSUMING FLUORESCENCE SENSOR FOR REAL TIME INTRAVASCULAR GLUCOSE MEASUREMENT | GLUMETRICS, INC. (US) | 2009-01-15 | — | — | US | disclosed |
| US-20080188722-A1 | OPTICAL DETERMINATION OF PH AND GLUCOSE | MEDTRONIC MINIMED, INC. | 2008-08-07 | — | — | US | disclosed |
| US-20080188725-A1 | OPTICAL SYSTEMS AND METHODS FOR RATIOMETRIC MEASUREMENT OF BLOOD GLUCOSE CONCENTRATION | MEDTRONIC MINIMED, INC. | 2008-08-07 | — | — | US | disclosed |