Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.53 |
| ▸ | HTR6 | P50406 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6641847 | 0.85 | FFAR1 (0.48) | ALDH1A1FFAR1PPARDESR1ESR2 | |
| SCHEMBL2033257 | 0.79 | ALDH1A1 (0.50) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL10331877 | 0.79 | ALDH1A1 (0.50) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL13550403 | 0.79 | ALDH1A1 (0.49) | ALDH1A1SRD5A1SRD5A2KDM4EMAPT | |
| SCHEMBL785696 | 0.79 | ALDH1A1 (0.49) | ALDH1A1SRD5A1SRD5A2KDM4EMAPT | |
| SCHEMBL8189658 | 0.79 | ALDH1A1 (0.49) | ALDH1A1SRD5A1SRD5A2KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL785877 | 0.78 | ALDH1A1 (0.47) | ALDH1A1SRD5A1SRD5A2KDM4EMAPT | |
| SCHEMBL5712647 | 0.77 | ESR1 (0.66) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL29726906 | 0.77 | ALDH1A1 (0.50) | ALDH1A1SRD5A1SRD5A2KDM4EMAPT | |
| SCHEMBL29726931 | 0.76 | ALDH1A1 (0.49) | ALDH1A1SRD5A1SRD5A2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010123017-A1 | TETRAZOLE COMPOUND | アステラス製薬株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |