Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | TACR2 | P21452 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | TAC3 | Q9UHF0 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13093494 | 0.83 | SLC6A4 (0.46) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL13092909 | 0.83 | SLC6A4 (0.46) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL13092908 | 0.83 | SLC6A4 (0.46) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5657812 | 0.80 | ITGA4 (0.44) | TACR1MC4R | |
| SCHEMBL5972730 | 0.80 | ITGA4 (0.44) | TACR1MC4R | |
| SCHEMBL5657809 | 0.80 | ITGA4 (0.44) | TACR1MC4R | |
| SCHEMBL830669 | 0.80 | POLB (0.56) | SLC6A4SLC6A3SLC6A2TACR1MC4R | |
| SCHEMBL2297284 | 0.80 | POLB (0.56) | SLC6A4SLC6A3SLC6A2TACR1MC4R | |
| SCHEMBL830668 | 0.80 | POLB (0.56) | SLC6A4SLC6A3SLC6A2TACR1MC4R | |
| SCHEMBL20805978 | 0.77 | MC4R (0.51) | SLC6A4SLC6A3SLC6A2MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010123006-A1 | PYRROLIDINE COMPOUND | 武田薬品工業株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |