Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 19/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515774 | 0.84 | GPR119 (0.52) | GPR119 | |
| Hydrochloric Acid SCHEMBL515112 | 0.83 | GPR119 (0.51) | GPR119 | |
| SCHEMBL515348 | 0.83 | GPR119 (0.68) | GPR119 | |
| SCHEMBL13092835 | 0.80 | GPR119 (0.49) | GPR119MKNK1MKNK2 | |
| SCHEMBL515188 | 0.79 | GPR119 (0.49) | GPR119 | |
| SCHEMBL13092793 | 0.79 | GPR119 (0.49) | GPR119 | |
| SCHEMBL13092821 | 0.79 | HTT (0.49) | GPR119MKNK1MKNK2 | |
| SCHEMBL13093288 | 0.79 | GPR119 (0.48) | GPR119MKNK1MKNK2 | |
| SCHEMBL13092832 | 0.78 | GPR119 (0.51) | GPR119 | |
| SCHEMBL13092789 | 0.78 | GPR119 (0.51) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010119881-A1 | INDOLINE COMPOUND | 第一三共株式会社 (JP) | 2010-10-21 | — | — | WO | disclosed |