⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935410 | 1.00 | — | — | |
| SCHEMBL20956305 | 0.86 | — | — | |
| SCHEMBL10007558 | 0.74 | — | — | |
| SCHEMBL982080 | 0.69 | — | — | |
| SCHEMBL12654038 | 0.69 | — | — | |
| SCHEMBL19574053 | 0.66 | KDM4E (0.33) | — | |
| SCHEMBL1457003 | 0.65 | — | — | |
| SCHEMBL874698 | 0.65 | — | — | |
| SCHEMBL7077764 | 0.65 | — | — | |
| SCHEMBL29308164 | 0.65 | MEN1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250270596-A1 | MEVALONATE DERIVATIVES AND METHODS FOR MAKING THE SAME | UNIV DUKE (US) | 2025-08-28 | — | — | US | claimed |
| US-11254786-B2 | Multifunctional degradable nanoparticles with control over size and functionalities | VANDERBILT UNIVERSITY (US) | 2022-02-22 | — | — | US | disclosed |
| US-10442890-B2 | Multifunctional degradable nanoparticles with control over size and functionalities | VANDERBILT UNIVERSITY (US) | 2019-10-15 | — | — | US | disclosed |
| EP-2209496-B1 | MULTIFUNCTIONAL DEGRADABLE NANOPARTICLES WITH CONTROL OVER SIZE AND FUNCTIONALITIES | UNIV VANDERBILT (US) | 2019-05-08 | — | — | EP | disclosed |
| US-20180142061-A1 | Multifunctional Degradable Nanoparticles with Control over Size and Functionalities | UNIV VANDERBILT (US) | 2018-05-24 | — | — | US | disclosed |
| US-9856348-B2 | Multifunctional degradable nanoparticles with control over size and functionalities | VANDERBILT UNIVERSITY (US) | 2018-01-02 | — | — | US | disclosed |
| US-20160237208-A1 | Multifunctional Degradable Nanoparticles with Control over Size and Functionalities | UNIV VANDERBILT (US) | 2016-08-18 | — | — | US | disclosed |
| US-8492510-B2 | Multifunctional degradable nanoparticles with control over size and functionalities | VANDERBILT UNIVERSITY (US) | 2013-07-23 | — | — | US | disclosed |
| US-20130142733-A1 | MULTIFUNCTIONAL DEGRADABLE NANOPARTICLES WITH CONTROL OVER SIZE AND FUNCTIONALITIES | VANDERBILT UNIVERSITY (US) | 2013-06-06 | — | — | US | disclosed |
| US-20110274620-A1 | MULTIFUNCTIONAL DEGRADABLE NANOPARTICLES WITH CONTROL OVER SIZE AND FUNCTIONALITIES | NATIONAL SCIENCE FOUNDATION | 2011-11-10 | — | — | US | disclosed |
| US-20110257343-A1 | Multifunctional Degradable Nanoparticles with Control over Size and Functionalities | VANDERBILT UNIVERSITY | 2011-10-20 | — | — | US | disclosed |
| US-7935782-B2 | Multifunctional degradable nanoparticles with control over size and functionalities | VANDERBILT UNIVERSITY (US) | 2011-05-03 | — | — | US | disclosed |
| EP-2209496-A2 | MULTIFUNCTIONAL DEGRADABLE NANOPARTICLES WITH CONTROL OVER SIZE AND FUNCTIONALITIES | VANDERBILT UNIVERSITY (US) | 2010-07-28 | — | — | EP | disclosed |
| US-20090306335-A1 | MULTIFUNCTIONAL DEGRADABLE NANOPARTICLES WITH CONTROL OVER SIZE AND FUNCTIONALITIES | NATIONAL SCIENCE FOUNDATION | 2009-12-10 | — | — | US | disclosed |
| WO-2009061854-A2 | MULTIFUNCTIONAL DEGRADABLE NANOPARTICLES WITH CONTROL OVER SIZE AND FUNCTIONALITIES | VANDERBILT UNIVERSITY (US) | 2009-05-14 | — | — | WO | disclosed |
| US-5504219-A | Optically active compounds and intermediates thereof, and process for manufacturing same | ASAHI DENKA KOGYO K.K. (JP) | 1996-04-02 | — | — | US | disclosed |
| US-5352845-A | Process for manufacture of optically active saturated compounds | ASAHI DENKA KOGYO K.K. (JP) | 1994-10-04 | — | — | US | disclosed |
| US-5262552-A | Optically active compounds and intermediates thereof, and process for manufacturing same | ASAHI DENKA KOGYO K.K. (JP) | 1993-11-16 | — | — | US | disclosed |