Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 19/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12711488 | 0.86 | BDKRB2 (0.51) | BDKRB2 | |
| SCHEMBL14038585 | 0.84 | BDKRB2 (0.57) | BDKRB2 | |
| SCHEMBL12711809 | 0.84 | BDKRB2 (0.46) | BDKRB2 | |
| SCHEMBL13093059 | 0.83 | BDKRB2 (0.47) | BDKRB2 | |
| SCHEMBL13093418 | 0.82 | BDKRB2 (0.50) | BDKRB2HPGDTSHR | |
| SCHEMBL12711825 | 0.82 | BDKRB2 (0.49) | BDKRB2 | |
| SCHEMBL13093405 | 0.82 | BDKRB2 (0.49) | BDKRB2 | |
| SCHEMBL12711395 | 0.81 | BDKRB2 (0.52) | BDKRB2 | |
| SCHEMBL13093009 | 0.81 | BDKRB2 (0.52) | BDKRB2 | |
| SCHEMBL12711858 | 0.81 | BDKRB2 (0.47) | BDKRB2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144897-B1 | 8-OXY-QUINOLINE DERIVATIVES AS BRADYKININ B2 RECEPTOR MODULATORS | JERINI AG (DE) | 2010-10-20 | — | — | EP | disclosed |