Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 11/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 11/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 9/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11935114 | 0.87 | SPHK1 (0.51) | MEN1KMT2AS1PR1S1PR3S1PR2 | |
| SCHEMBL11934726 | 0.87 | S1PR1 (0.46) | MEN1KMT2AS1PR1S1PR3S1PR2 | |
| SCHEMBL13100484 | 0.86 | HDAC6 (0.55) | MEN1KMT2AS1PR1S1PR3S1PR2 | |
| SCHEMBL16480073 | 0.80 | LMNA (0.49) | MEN1KMT2AHDAC6LMNALTA4H | |
| SCHEMBL13972889 | 0.79 | PLK1 (0.55) | MEN1KMT2AALDH1A1PLK1 | |
| SCHEMBL17656855 | 0.79 | CXCR4 (0.59) | MEN1KMT2AHDAC6LTA4H | |
| SCHEMBL17090465 | 0.79 | NPY5R (0.41) | MEN1KMT2AS1PR1S1PR3S1PR2 | |
| SCHEMBL17090119 | 0.79 | NPY5R (0.41) | MEN1KMT2AS1PR1S1PR3S1PR2 | |
| SCHEMBL13438845 | 0.79 | MEN1 (0.38) | MEN1KMT2AS1PR1S1PR3S1PR2 | |
| SCHEMBL13564848 | 0.79 | NPY5R (0.41) | MEN1KMT2AS1PR1S1PR3S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100273842-A1 | AMINE DERIVATIVES HAVING NPY Y5 RECEPTOR ANTAGONISTIC ACTIVITY AND THE USES THEREOF | SHIONOGI & CO., LTD. (JP) | 2010-10-28 | — | — | US | disclosed |
| US-20100267945-A1 | AMINE DERIVATIVE HAVING NPY Y5 RECEPTOR ANTAGONISTIC ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273842-A1 | AMINE DERIVATIVES HAVING NPY Y5 RECEPTOR ANTAGONISTIC ACTIVITY AND THE USES THEREOF | NPY5R, NPY1R, NPY2R | MEN1 2486/4885KMT2A 2321/4885S1PR1 436/4885 |
| US-20100267945-A1 | AMINE DERIVATIVE HAVING NPY Y5 RECEPTOR ANTAGONISTIC ACTIVITY | NPY5R, NPY1R, NPY2R | MEN1 1233/4885KMT2A 2517/4885S1PR1 303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.