Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13095785 | 0.87 | HTT (0.48) | HTTGAATSHRTRPV1NAMPT | |
| SCHEMBL790701 | 0.86 | HTT (0.44) | HTTGAATSHRTRPV1NAMPT | |
| SCHEMBL12978221 | 0.76 | HTT (0.39) | HTTGAATSHRTRPV1NAMPT | |
| SCHEMBL12978089 | 0.76 | LIPE (0.43) | HTTNPC1RAB9AKMT2A | |
| SCHEMBL790234 | 0.71 | HTT (0.67) | HTTGAATSHRTRPV1CYP3A4 | |
| SCHEMBL13095774 | 0.70 | HTT (0.65) | HTTGAATSHRTRPV1CYP3A4 | |
| SCHEMBL790267 | 0.69 | HTT (0.64) | HTTGAATSHRTRPV1CYP3A4 | |
| SCHEMBL790147 | 0.68 | HTT (0.61) | HTTGAATSHRTRPV1CYP3A4 | |
| SCHEMBL789977 | 0.68 | HTT (0.61) | HTTGAATSHRTRPV1CYP3A4 | |
| SCHEMBL791684 | 0.68 | HTT (0.61) | HTTGAATSHRTRPV1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2236505-A1 | Acylated aminopyridines and pyridazines as insecticides | Bayer CropScience AG (DE) | 2010-10-06 | — | — | EP | disclosed |