Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 19/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13096116 | 0.87 | APP (0.71) | APPMAPT | |
| SCHEMBL13096128 | 0.84 | APP (0.62) | APPMAPTSNCA | |
| SCHEMBL2832302 | 0.82 | APP (1.00) | APP | |
| SCHEMBL13096120 | 0.81 | APP (0.70) | APP | |
| SCHEMBL12973237 | 0.81 | APP (0.78) | APPMAPTSNCA | |
| SCHEMBL11303203 | 0.79 | APP (0.83) | APPMAPTSNCA | |
| SCHEMBL12973263 | 0.79 | APP (0.83) | APPMAPTSNCA | |
| SCHEMBL2829057 | 0.78 | APP (1.00) | APP | |
| SCHEMBL12973266 | 0.76 | APP (0.68) | APPMAPTSNCA | |
| SCHEMBL13207855 | 0.75 | APP (0.86) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100272642-A1 | PET PROBE HAVING AN ALKOXY GROUP SUBSTITUTED BY FLUORINE AND HYDROXY GROUP | TOHOKU UNIVERSITY (JP) | 2010-10-28 | — | — | US | disclosed |
| US-20100272642-A1 | PET PROBE HAVING AN ALKOXY GROUP SUBSTITUTED BY FLUORINE AND HYDROXY GROUP | TOHOKU UNIVERSITY (JP) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100272642-A1 | PET PROBE HAVING AN ALKOXY GROUP SUBSTITUTED BY FLUORINE AND HYDROXY GROUP | PIGO, HTT, SLCO2B1 | APP 34/4885MAPT 188/4885SNCA 322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.