Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 19/20 | 0.78 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2832302 | 0.88 | APP (1.00) | APP | |
| SCHEMBL13207855 | 0.86 | APP (0.86) | APP | |
| SCHEMBL13863149 | 0.84 | APP (0.59) | APPMAPTSNCA | |
| SCHEMBL13096116 | 0.82 | APP (0.71) | APPMAPT | |
| SCHEMBL2829057 | 0.81 | APP (1.00) | APP | |
| SCHEMBL13096119 | 0.81 | APP (0.70) | APPMAPTSNCA | |
| SCHEMBL11303203 | 0.76 | APP (0.83) | APPMAPTSNCA | |
| SCHEMBL12973263 | 0.76 | APP (0.83) | APPMAPTSNCA | |
| SCHEMBL13431717 | 0.73 | APP (0.73) | APPMAPTSNCA | |
| SCHEMBL29690309 | 0.72 | APP (1.00) | APPMAPTSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8465726-B2 | Stilbene derivatives and their use for binding and imaging amyloid plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-06-18 | — | — | US | disclosed |
| US-7858072-B2 | Stilbene derivatives and their use for binding and imaging amyloid plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-12-28 | — | — | US | disclosed |
| US-7807135-B2 | Stilbene derivatives and their use for binding and imaging amyloid plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-10-05 | — | — | US | disclosed |