Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.70 |
| ▸ | CYP2A6 | P11509 | 7/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.49 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 2/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30473695 | 0.83 | PTGS1 (0.52) | PTGS2PTGS1CYP2A6CYP3A4CYP2E1 | |
| SCHEMBL4888583 | 0.83 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL4888586 | 0.82 | PTGS2 (0.80) | PTGS2PTGS1CYP2A6CYP3A4CYP2C9 | |
| SCHEMBL6172129 | 0.79 | CCR1 (0.53) | PTGS2PTGS1CYP2A6CYP3A4CYP2E1 | |
| SCHEMBL13086838 | 0.79 | PTGS2 (0.48) | PTGS2PTGS1CYP2A6CYP3A4MAP2K4 | |
| SCHEMBL10205830 | 0.78 | KMT2A (0.53) | PTGS2PTGS1CYP2A6ALDH1A1CYP1A2 | |
| Toluene SCHEMBL28031482 | 0.77 | CYP2A6 (0.60) | PTGS2PTGS1CYP2A6CYP3A4MAP2K4 | |
| Ethane SCHEMBL28235431 | 0.77 | PTGS2 (0.65) | PTGS2PTGS1CYP2A6CYP3A4CYP2E1 | |
| SCHEMBL3424504 | 0.77 | CYP2A6 (0.56) | CYP2A6CYP3A4MAP2K4CYP2E1CYP2D6 | |
| SCHEMBL25871383 | 0.77 | CYP2A6 (0.56) | PTGS2CYP2A6CYP3A4MAP2K4CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100261679-A1 | CSF-1R, Inhibitors, Compositions, and Methods of Use | NOVARTIS AG (CH) | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261679-A1 | CSF-1R, Inhibitors, Compositions, and Methods of Use | CSF1R, CSF3R, MSR1 | PTGS2 834/4885PTGS1 314/4885CYP2A6 3442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.