Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.53 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | PRKDC | P78527 | 4/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NAAA | Q02083 | 2/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | SNRNP200 | O75643 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | LIPC | P11150 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13097458 | 0.89 | DDB1 (0.57) | F10ALDH1A1DDB1CRBNGRM5 | |
| SCHEMBL19086546 | 0.87 | F10 (0.54) | F10ALDH1A1DDB1CRBNPRKDC | |
| SCHEMBL5737605 | 0.84 | GRM5 (0.59) | DDB1CRBNGRM5ALOX5NAAA | |
| SCHEMBL3091096 | 0.83 | MAPT (0.43) | F10ALDH1A1DDB1CRBNGRM5 | |
| SCHEMBL13097411 | 0.81 | GRM5 (0.56) | ALDH1A1DDB1CRBNGRM5ALOX5 | |
| SCHEMBL13107121 | 0.80 | MAP4K1 (0.48) | ALDH1A1 | |
| SCHEMBL13097446 | 0.80 | MAP4K1 (0.42) | F10ALDH1A1DDB1CRBNGRM5 | |
| SCHEMBL13097167 | 0.80 | GRM5 (0.54) | ALDH1A1DDB1CRBNGRM5ALOX5 | |
| SCHEMBL1263059 | 0.79 | AGXT (0.61) | ALDH1A1GRM5PRKDCALOX5ATM | |
| SCHEMBL13097418 | 0.79 | CACNA2D1 (0.54) | ALDH1A1DDB1CRBNGRM5ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367702-B2 | Quinolone derivative | ASTELLAS PHARMA INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20100256113-A1 | QUINOLONE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256113-A1 | QUINOLONE DERIVATIVE | NQO1, NQO2, NADK | F10 1624/4885ALDH1A1 524/4885DDB1 2911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.