Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13097258 | 0.87 | F10 (0.55) | F10MCHR1PRKDCDDB1CRBN | |
| SCHEMBL5697582 | 0.82 | MMP13 (0.54) | MCHR1PTGS2DDB1CRBNMAPT | |
| SCHEMBL198132 | 0.80 | PTGS2 (0.57) | F10PTGS2KMT2A | |
| SCHEMBL5569349 | 0.80 | SMN1; SMN2 (0.55) | MCHR1KDM1AALDH1A1MAPTGAA | |
| SCHEMBL28211954 | 0.79 | KMT2A (0.62) | MCHR1PTGS2PRKDCEGFRALDH1A1 | |
| SCHEMBL2178470 | 0.77 | F10 (0.73) | F10KDM1APTGS2PRKDCALDH1A1 | |
| SCHEMBL14830455 | 0.77 | F10 (0.53) | F10KDM1APTGS2KMT2A | |
| SCHEMBL5737920 | 0.77 | PTGS2 (0.55) | F10KDM1APTGS2GAAKMT2A | |
| SCHEMBL13097458 | 0.76 | DDB1 (0.57) | F10MCHR1PRKDCDDB1CRBN | |
| SCHEMBL2537613 | 0.76 | PTGS2 (0.66) | F10PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3190104-B1 | QUINOLINONE COMPOUND AND USE THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2021-10-27 | — | — | EP | disclosed |
| US-10065928-B2 | Quinolinone compound and use thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2018-09-04 | — | — | US | disclosed |
| US-20170247332-A1 | QUINOLINONE COMPOUND AND USE THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-08-31 | — | — | US | disclosed |
| EP-3190104-A1 | QUINOLINONE COMPOUND AND USE THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2017-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170247332-A1 | QUINOLINONE COMPOUND AND USE THEREOF | HIF1AN, HIF1A, EGLN2 | F10 1853/4885MCHR1 1286/4885KDM1A 917/4885 |
| US-10065928-B2 | Quinolinone compound and use thereof | HIF1AN, HIF1A, EGLN2 | F10 1853/4885MCHR1 1286/4885KDM1A 917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.