Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.55 |
| ▸ | LTA4H | P09960 | 4/20 | 0.53 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27831281 | 0.93 | NR5A1 (0.63) | PDK2LTA4HNR5A1PTPN11TP53 | |
| SCHEMBL17445910 | 0.93 | PDK2 (0.50) | PDK2LTA4HNR5A1MEN1KMT2A | |
| SCHEMBL17445908 | 0.93 | PDK2 (0.50) | PDK2LTA4HNR5A1MEN1KMT2A | |
| SCHEMBL12228055 | 0.89 | PDK2 (0.52) | PDK2LTA4HTSHRMEN1KMT2A | |
| SCHEMBL17050179 | 0.89 | PDK2 (0.52) | PDK2LTA4HTSHRMEN1KMT2A | |
| SCHEMBL28463849 | 0.88 | PDK2 (0.46) | PDK2LTA4HTP53TSHRCYP2C9 | |
| SCHEMBL28471347 | 0.87 | PDK2 (0.45) | PDK2LTA4HNR5A1CYP2C9CYP2C19 | |
| SCHEMBL28262297 | 0.85 | PDK2 (0.60) | PDK2LTA4HNR5A1PTPN11TP53 | |
| SCHEMBL1305002 | 0.85 | PDK2 (0.60) | PDK2LTA4HNR5A1PTPN11TP53 | |
| SCHEMBL16902914 | 0.85 | NR5A1 (0.50) | PDK2LTA4HNR5A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100270537-A1 | OPTOELECTRONIC DEVICES AND ORGANIC COMPOUNDS USED THEREIN | GENERAL ELECTRIC COMPANY (US) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100270537-A1 | OPTOELECTRONIC DEVICES AND ORGANIC COMPOUNDS USED THEREIN | AOC3, C3AR1, AOC2 | PDK2 1752/4885LTA4H 950/4885NR5A1 778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.