⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18579637 | 1.00 | — | — | |
| SCHEMBL9071081 | 1.00 | — | — | |
| SCHEMBL23829867 | 0.83 | MME (0.47) | — | |
| SCHEMBL680803 | 0.82 | — | — | |
| SCHEMBL27504736 | 0.80 | MME (0.43) | — | |
| SCHEMBL5304252 | 0.79 | TAAR1 (0.50) | — | |
| SCHEMBL4205089 | 0.79 | DRD2 (0.42) | — | |
| SCHEMBL5536860 | 0.78 | — | — | |
| SCHEMBL18875010 | 0.78 | — | — | |
| SCHEMBL12251318 | 0.78 | TAAR1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250382306-A1 | HETEROCYCLIC COMPOUND AS TAAR1 LIGAND AGONIST | Shandong luye pharmaceutical co ltd (CN) | 2025-12-18 | — | — | US | disclosed |
| EP-4545534-A1 | HETEROCYCLIC COMPOUND AS TAAR1 LIGAND AGONIST | Shandong Luye Pharmaceutical Co., Ltd. (CN) | 2025-04-30 | — | — | EP | disclosed |
| WO-2025049326-A1 | TRICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | BIOCRYST PHARMACEUTICALS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |
| WO-2023246872-A1 | HETEROCYCLIC COMPOUND AS TAAR1 LIGAND AGONIST | 山东绿叶制药有限公司 | 2023-12-28 | — | — | WO | disclosed |
| CN-110337440-B | Compounds useful for inhibition of ROR-gamma-t | 伊莱利利公司 | 2021-08-03 | — | — | CN | disclosed |
| US-11008336-B2 | Compounds useful for inhibiting RORγt | ELI LILLY AND COMPANY (US) | 2021-05-18 | — | — | US | disclosed |
| US-11008336-B2 | Compounds useful for inhibiting RORγt | ELI LILLY AND COMPANY (US) | 2021-05-18 | — | — | US | disclosed |
| EP-3589638-B1 | COMPOUNDS USEFUL FOR INHIBITING ROR-GAMMA-T | LILLY CO ELI (US) | 2021-04-07 | — | — | EP | disclosed |
| EP-3589638-B1 | COMPOUNDS USEFUL FOR INHIBITING ROR-GAMMA-T | LILLY CO ELI (US) | 2021-04-07 | — | — | EP | disclosed |
| CN-108026112-B | Compounds for inhibition of ROR-gamma-T | 伊莱利利公司 | 2020-04-10 | — | — | CN | disclosed |
| US-20170066781-A1 | COMPOUNDS USEFUL FOR INHIBITING ROR-GAMMA-T | LILLY CO ELI (US) | 2017-03-09 | — | — | US | disclosed |
| US-20170066781-A1 | COMPOUNDS USEFUL FOR INHIBITING ROR-GAMMA-T | LILLY CO ELI (US) | 2017-03-09 | — | — | US | disclosed |
| US-8053378-B2 | Modified phenolic resin, epoxy resin composition containing the same, and prepreg containing the composition | MITSUI CHEMICALS, INC. (JP) | 2011-11-08 | — | — | US | disclosed |
| CN-101084250-B | Modified phenol resin, epoxy resin composition containing the same, and prepreg using the composition | MITSUI CHEMICALS INC | 2011-06-15 | — | — | CN | disclosed |
| US-20080044667-A1 | Modified Phenolic Resin, Epoxy Resin Composition Containing the Same, and Prepreg Containing the Composition | MITSUI CHEMICALS, INC. (JP) | 2008-02-21 | — | — | US | disclosed |
| CN-101084250-A | Modified phenol resin, epoxy resin composition containing the same, and prepreg using the composition | MITSUI CHEMICALS INC (JP) | 2007-12-05 | — | — | CN | disclosed |
| US-5679670-A | CONTROLLING INTRAOCULAR PRESSURE | ALCON LABORATORIES, INC. (US) | 1997-10-21 | — | — | US | disclosed |
| US-5378703-A | FOR CONTROLLING INTRAOCULAR PRESSURE | ALCON LABORATORIES, INC. (US) | 1995-01-03 | — | — | US | disclosed |
| CN-1019489-B | Process for preparing optically active furoimidazole-2, 4-diones | HOFFMANN LA ROCHE (CH) | 1992-12-16 | — | — | CN | disclosed |
| CN-85105078-A | The manufacture method of lactone | — | 1986-12-31 | — | — | CN | disclosed |