Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10280195 | 0.85 | FFAR1 (0.43) | FFAR1 | |
| SCHEMBL12309941 | 0.82 | FFAR1 (0.39) | FFAR1 | |
| SCHEMBL9888234 | 0.82 | FFAR1 (0.39) | FFAR1 | |
| SCHEMBL3397660 | 0.82 | FFAR1 (0.35) | FFAR1 | |
| SCHEMBL12513161 | 0.81 | FFAR1 (0.36) | FFAR1 | |
| SCHEMBL8270153 | 0.80 | FFAR1 (0.37) | FFAR1 | |
| SCHEMBL12826986 | 0.80 | FFAR1 (0.37) | FFAR1 | |
| SCHEMBL4251935 | 0.80 | FFAR1 (0.38) | FFAR1 | |
| SCHEMBL12568451 | 0.79 | JAK2 (0.37) | FFAR1 | |
| SCHEMBL4258112 | 0.79 | FFAR1 (0.39) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299055-B2 | 8-substituted isoquinoline derivative and the use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2012-10-30 | — | — | US | disclosed |
| US-20100261701-A1 | 8-Substituted isoquinoline derivative and the use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261701-A1 | 8-Substituted isoquinoline derivative and the use thereof | RELA, NFKBIA, NFKB2 | FFAR1 2209/4885KMT2A 637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.