⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12638433 | 0.90 | CA12 (0.48) | — | |
| SCHEMBL9407540 | 0.89 | CA12 (0.50) | — | |
| SCHEMBL343532 | 0.88 | CA12 (0.50) | — | |
| SCHEMBL13171255 | 0.83 | TSHR (0.44) | — | |
| SCHEMBL9192134 | 0.83 | GABBR2 (0.42) | — | |
| SCHEMBL11168256 | 0.82 | — | — | |
| SCHEMBL4917007 | 0.82 | — | — | |
| SCHEMBL26489041 | 0.81 | TSHR (0.50) | — | |
| SCHEMBL13118766 | 0.81 | GABBR2 (0.35) | — | |
| SCHEMBL9323831 | 0.80 | GABBR2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140044671-A1 | AMINE CONDENSATION POLYMERS AS PHOSPHATE SEQUESTRANTS | GENZYME CORPORATION (US) | 2014-02-13 | — | — | US | disclosed |
| US-20100254935-A1 | Amine condensation polymers as phosphate sequestrants | GENZYME CORPORATION (US) | 2010-10-07 | — | — | US | disclosed |
| US-20080085259-A1 | Amine condensation polymers as phosphate sequestrants | GENZYME CORPORATION | 2008-04-10 | — | — | US | disclosed |