Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 14/20 | 1.00 |
| ▸ | PTGER3 | P43115 | 12/20 | 1.00 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1310059 | 1.00 | PTGER2 (1.00) | PTGER2PTGER3PTGDRTBXA2RPTGER1 | |
| SCHEMBL2992422 | 1.00 | PTGER2 (1.00) | PTGER2PTGER3PTGDRTBXA2RPTGER1 | |
| SCHEMBL2991664 | 0.85 | PTGER2 (0.74) | PTGER2PTGER3PTGDRTBXA2RNR1H4 | |
| SCHEMBL1311310 | 0.85 | PTGER2 (0.74) | PTGER2PTGER3PTGDRTBXA2RNR1H4 | |
| SCHEMBL13667619 | 0.84 | PTGER2 (0.72) | PTGER2PTGER3PTGDRTBXA2RPTGER1 | |
| SCHEMBL13674239 | 0.84 | PTGER2 (0.72) | PTGER2PTGER3PTGDRTBXA2RPTGER1 | |
| SCHEMBL13227567 | 0.83 | PTGER2 (0.71) | PTGER2PTGER3PTGDRPTGER1PTGER4 | |
| SCHEMBL13181263 | 0.83 | PTGER2 (0.71) | PTGER2PTGER3PTGDRPTGER1PTGER4 | |
| SCHEMBL13385600 | 0.81 | PTGER2 (0.69) | PTGER2PTGER3PTGDRTBXA2RPTGER1 | |
| SCHEMBL12112053 | 0.81 | PTGER2 (0.67) | PTGER2PTGER3PTGDRNR1H4PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7476747-B2 | Substituted gamma lactams as therapeutic agents | ALLERGAN, INC. (US) | 2009-01-13 | — | — | US | claimed |
| US-20070287742-A1 | Subsitituted Gamma Lactams As Therapeutic Agents | ALLERGAN, INC. (US) | 2007-12-13 | — | — | US | claimed |
| EP-1856042-A2 | SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS | Allergan, Inc. (US) | 2007-11-21 | — | — | EP | claimed |
| WO-2006098918-A2 | SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS | ALLERGAN, INC. (US) | 2006-09-21 | — | — | WO | claimed |
| CN-105520941-B | Substituted gamma lactams as therapeutic agents | 阿勒根公司 | 2020-05-01 | — | — | CN | disclosed |
| EP-1856042-B1 | SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS | ALLERGAN INC (US) | 2012-06-27 | — | — | EP | disclosed |
| US-20110275692-A1 | SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS | ALLERGAN, INC. (US) | 2011-11-10 | — | — | US | disclosed |
| US-20110275692-A1 | SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS | ALLERGAN, INC. (US) | 2011-11-10 | — | — | US | disclosed |
| US-20110275692-A1 | SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS | ALLERGAN, INC. (US) | 2011-11-10 | — | — | US | disclosed |
| US-8044092-B2 | Therapeutic compounds | ALLERGAN, INC. (US) | 2011-10-25 | — | — | US | disclosed |
| US-8044092-B2 | Therapeutic compounds | ALLERGAN, INC. (US) | 2011-10-25 | — | — | US | disclosed |
| US-7973071-B2 | Substituted gamma lactams as therapeutic agents | ALLERGAN, INC. (US) | 2011-07-05 | — | — | US | disclosed |
| US-20070287742-A1 | Subsitituted Gamma Lactams As Therapeutic Agents | ALLERGAN, INC. (US) | 2007-12-13 | — | — | US | disclosed |
| US-20070287742-A1 | Subsitituted Gamma Lactams As Therapeutic Agents | ALLERGAN, INC. (US) | 2007-12-13 | — | — | US | disclosed |
| EP-1856042-A2 | SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS | Allergan, Inc. (US) | 2007-11-21 | — | — | EP | disclosed |
| US-20070265330-A1 | SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS | OLD DAVID W | 2007-11-15 | — | — | US | disclosed |
| US-20070265330-A1 | SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS | OLD DAVID W | 2007-11-15 | — | — | US | disclosed |
| US-20070203222-A1 | SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS | ALLERGAN, INC. | 2007-08-30 | — | — | US | disclosed |
| US-20070203222-A1 | SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS | ALLERGAN, INC. | 2007-08-30 | — | — | US | disclosed |
| WO-2006098918-A2 | SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS | ALLERGAN, INC. (US) | 2006-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203222-A1 | SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS | GLA, GANAB, GGH | PTGER2 3074/4885PTGER3 2826/4885PTGDR 1712/4885 |
| US-20110275692-A1 | SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS | GLA, GUSB, GANAB | PTGER2 2460/4885PTGER3 2410/4885PTGDR 961/4885 |
| US-20070265330-A1 | SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS | GLA, GUSB, GANAB | PTGER2 2460/4885PTGER3 2410/4885PTGDR 961/4885 |
| US-20070287742-A1 | Subsitituted Gamma Lactams As Therapeutic Agents | SI, MGAM, GLA | PTGER2 3011/4885PTGER3 2973/4885PTGDR 1718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.