Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.39 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13102004 | 0.91 | SLC2A1 (0.43) | SLC2A1SLC2A3SLC2A4CYP3A4ALDH1A1 | |
| SCHEMBL13102012 | 0.89 | ERCC1 (0.40) | ERCC1ERCC4PARP14CYP3A4ROCK1 | |
| SCHEMBL13102384 | 0.86 | CYP1A2 (0.48) | CYP3A4ALDH1A1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL13102460 | 0.85 | ERCC1 (0.44) | ERCC1ERCC4PARP14CYP3A4ROCK1 | |
| SCHEMBL13101686 | 0.83 | ALDH1A1 (0.43) | CYP3A4ALDH1A1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL13102099 | 0.81 | ALDH1A1 (0.42) | ERCC1ERCC4CYP3A4ROCK1ALDH1A1 | |
| SCHEMBL13102097 | 0.80 | ERCC1 (0.42) | ERCC1ERCC4PARP14SLC2A1SLC2A3 | |
| SCHEMBL13102006 | 0.80 | CTNNB1 (0.44) | PARP14SLC2A1SLC2A3SLC2A4ALDH1A1 | |
| SCHEMBL13102272 | 0.79 | ALDH1A1 (0.48) | CYP3A4ALDH1A1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL13101684 | 0.76 | ALDH1A1 (0.48) | CYP3A4ALDH1A1KDM4ECYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329713-B2 | Fused ring heterocycles as potassium channel modulators | ICAGEN INC. (US) | 2012-12-11 | — | — | US | disclosed |
| US-20100273784-A1 | FUSED RING HETEROCYCLES AS POTASSIUM CHANNEL MODULATORS | ICAGEN, INC. (US) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273784-A1 | FUSED RING HETEROCYCLES AS POTASSIUM CHANNEL MODULATORS | KCNK17, KCNJ2, KCNJ1 | ERCC1 2046/4885ERCC4 2847/4885PARP14 1452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.