Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13106542 | 0.92 | GPBAR1 (0.42) | CYSLTR1GPBAR1CYSLTR2DHODHCYP2D6 | |
| SCHEMBL13097251 | 0.90 | MAOB (0.38) | MAPTKMT2ATDP1SMN1; SMN2 | |
| SCHEMBL13349888 | 0.87 | CYSLTR1 (0.55) | CYSLTR1GPBAR1CYSLTR2DHODHCYP2D6 | |
| SCHEMBL13106415 | 0.86 | CYSLTR2 (0.39) | CYSLTR1CYSLTR2CYP2D6MAPTLMNA | |
| SCHEMBL13107289 | 0.84 | CYSLTR2 (0.41) | CYSLTR1CYSLTR2CYP2D6MAPTLMNA | |
| SCHEMBL13107136 | 0.84 | ALDH1A1 (0.34) | DHODHCYP2D6MAPTMEN1KMT2A | |
| SCHEMBL13349923 | 0.83 | GPBAR1 (0.40) | CYSLTR1GPBAR1CYSLTR2DHODHCYP2D6 | |
| SCHEMBL13106608 | 0.82 | GPBAR1 (0.41) | CYSLTR1GPBAR1CYSLTR2DHODHCYP2D6 | |
| SCHEMBL13106235 | 0.82 | GPBAR1 (0.46) | CYSLTR1GPBAR1CYSLTR2DHODHCYP2D6 | |
| SCHEMBL13106245 | 0.82 | GPBAR1 (0.49) | CYSLTR1GPBAR1CYSLTR2DHODHCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367702-B2 | Quinolone derivative | ASTELLAS PHARMA INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20100256113-A1 | QUINOLONE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
| EP-2194044-A1 | QUINOLONE DERIVATIVE | Astellas Pharma Inc. (JP) | 2010-06-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256113-A1 | QUINOLONE DERIVATIVE | NQO1, NQO2, NADK | CYSLTR1 2160/4885GPBAR1 1262/4885CYSLTR2 2038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.