Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 9/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 6/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13106438 | 0.85 | MAPK8 (0.43) | MAPK8MAPK9MAPK10GAAGABRA1 | |
| SCHEMBL13106432 | 0.82 | MAPK8 (0.41) | MAPK8MAPK9MAPK10GAAGABRA1 | |
| SCHEMBL13106443 | 0.80 | GAA (0.36) | MAPK8MAPK9MAPK10GAASMN1; SMN2 | |
| SCHEMBL13106325 | 0.79 | ADORA2A (0.44) | MAPK8MAPK9MAPK10GAASMN1; SMN2 | |
| SCHEMBL13106366 | 0.77 | MAPK8 (0.36) | MAPK8MAPK9MAPK10GAAALDH1A1 | |
| SCHEMBL13106436 | 0.72 | MAPK8 (0.36) | MAPK8MAPK9MAPK10GAA | |
| SCHEMBL13106360 | 0.72 | MAPK8 (0.36) | MAPK8MAPK9MAPK10GAACYP2C9 | |
| SCHEMBL13106420 | 0.71 | MAPK8 (0.56) | MAPK8MAPK9MAPK10MAPTGABRA1 | |
| SCHEMBL13106457 | 0.70 | ADORA2A (0.39) | MAPK8MAPK9MAPK10GAASMN1; SMN2 | |
| SCHEMBL13106386 | 0.70 | GAA (0.40) | MAPK8MAPK9MAPK10GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7812045-B2 | Antifungal triazole derivatives | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2010-10-12 | — | — | US | disclosed |
| US-20080194661-A1 | Antifungal Triazole Derivatives | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194661-A1 | Antifungal Triazole Derivatives | ERG28, CYP51A1, CYP3A43 | MAPK8 3107/4885MAPK9 2234/4885MAPK10 4181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.