Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | TP53 | P04637 | 4/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.51 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10940970 | 0.90 | ALDH1A1 (0.44) | ALDH1A1TP53XDHNQO1MAPT | |
| SCHEMBL10943076 | 0.89 | MAPT (0.44) | ALDH1A1TP53XDHNQO1MAPT | |
| SCHEMBL11483014 | 0.83 | NQO1 (0.48) | ALDH1A1TP53XDHNQO1MAPT | |
| SCHEMBL11247874 | 0.83 | CACNA2D1 (0.55) | ALDH1A1TP53NQO1MAPTCACNA2D1 | |
| SCHEMBL13108716 | 0.82 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL11241755 | 0.81 | CACNA2D1 (0.47) | ALDH1A1TP53XDHNQO1MAPT | |
| SCHEMBL11863432 | 0.81 | CACNA2D1 (0.48) | ALDH1A1TP53XDHNQO1MAPT | |
| SCHEMBL13108714 | 0.80 | ALDH1A1 (0.56) | ALDH1A1TP53XDHMAPTKDM4E | |
| SCHEMBL1305539 | 0.80 | ALDH1A1 (0.56) | ALDH1A1TP53XDHMAPTKDM4E | |
| SCHEMBL11469872 | 0.80 | CACNA2D1 (0.48) | ALDH1A1TP53NQO1MAPTCACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816520-B2 | Such as 1,4-Bis[5,6-(4,4'-dihydroxy)-diphenyl-1,2,4-triazin-3-yl]benzene; cosmetics for human skin, hair | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2010-10-19 | — | — | US | disclosed |
| US-20080267892-A1 | Such as 1,4-Bis[5,6-(4,4'-dihydroxy)-diphenyl-1,2,4-triazin-3-yl]benzene; cosmetics for human skin, hair | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080267892-A1 | Such as 1,4-Bis[5,6-(4,4'-dihydroxy)-diphenyl-1,2,4-triazin-3-yl]benzene; cosmetics for human skin, hair | TYR, H1-0, TELO2 | ALDH1A1 785/4885TP53 137/4885XDH 542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.