Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 12/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 9/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13110464 | 0.96 | FFAR1 (0.46) | FFAR1PPARAPPARGPPARD | |
| SCHEMBL3450890 | 0.94 | FFAR1 (0.55) | FFAR1PPARAPPARGPPARD | |
| SCHEMBL3450429 | 0.89 | FFAR1 (0.54) | FFAR1PPARAPPARGPPARD | |
| SCHEMBL13110443 | 0.80 | FFAR1 (0.50) | FFAR1PPARD | |
| SCHEMBL3451532 | 0.79 | FFAR1 (0.58) | FFAR1PPARD | |
| SCHEMBL1746741 | 0.78 | FFAR1 (0.42) | FFAR1PPARAPPARGPPARDGSTO1 | |
| SCHEMBL3451333 | 0.76 | FFAR1 (0.48) | FFAR1MEN1KMT2ANPSR1 | |
| SCHEMBL3964811 | 0.75 | FFAR1 (0.63) | FFAR1PPARAPPARGPPARDGRIN1 | |
| SCHEMBL1745053 | 0.75 | FFAR1 (0.53) | FFAR1PPARAPPARGPPARDMEN1 | |
| SCHEMBL3450971 | 0.75 | FFAR1 (0.55) | FFAR1MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820837-B2 | ethyl {6-[(3-phenoxybenzyl)oxy]-3,4-dihydronaphthalen-1-yl}acetate; having a GPR40 receptor function modulating action and being useful as an insulin secretagogue or a pharmaceutical agent for the prophylaxis or treatment of diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-10-26 | — | — | US | disclosed |
| US-7820837-B2 | ethyl {6-[(3-phenoxybenzyl)oxy]-3,4-dihydronaphthalen-1-yl}acetate; having a GPR40 receptor function modulating action and being useful as an insulin secretagogue or a pharmaceutical agent for the prophylaxis or treatment of diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-10-26 | — | — | US | disclosed |