Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.53 |
| ▸ | GCK | P35557 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8258187 | 0.90 | F10 (0.55) | F10 | |
| SCHEMBL8251764 | 0.88 | F10 (0.52) | F10 | |
| SCHEMBL13110499 | 0.86 | F10 (0.51) | F10GCK | |
| SCHEMBL8260111 | 0.85 | F10 (0.51) | F10CHKA | |
| SCHEMBL13110503 | 0.84 | F10 (0.55) | F10CHKA | |
| SCHEMBL3449536 | 0.71 | F10 (0.54) | F10 | |
| SCHEMBL8259952 | 0.71 | F10 (0.78) | F10 | |
| SCHEMBL13395093 | 0.70 | F10 (0.70) | F10 | |
| SCHEMBL3313491 | 0.70 | F10 (0.70) | F10 | |
| SCHEMBL13110326 | 0.69 | F10 (0.62) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820699-B2 | Cyclic amines | HOFFMANN-LA ROCHE INC. (US) | 2010-10-26 | — | — | US | disclosed |
| US-7820699-B2 | Cyclic amines | HOFFMANN-LA ROCHE INC. (US) | 2010-10-26 | — | — | US | disclosed |