Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.72 |
| ▸ | PPARD | Q03181 | 14/20 | 0.72 |
| ▸ | FFAR1 | O14842 | 15/20 | 0.67 |
| ▸ | PPARA | Q07869 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13110586 | 0.95 | PPARG (0.73) | PPARGPPARDFFAR1PPARA | |
| Trifluoroacetic Acid SCHEMBL3450183 | 0.94 | PPARG (0.65) | PPARGPPARDFFAR1PPARA | |
| Trifluoroacetic Acid SCHEMBL3449858 | 0.90 | PPARG (0.66) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL3450186 | 0.86 | PPARG (0.54) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL3450988 | 0.83 | PPARD (0.95) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL3450733 | 0.83 | PPARD (1.00) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL3450439 | 0.83 | PPARG (0.78) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL3449862 | 0.81 | PPARG (0.55) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL3450263 | 0.80 | FFAR1 (0.63) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL13110585 | 0.80 | PPARD (0.61) | PPARGPPARDFFAR1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820837-B2 | ethyl {6-[(3-phenoxybenzyl)oxy]-3,4-dihydronaphthalen-1-yl}acetate; having a GPR40 receptor function modulating action and being useful as an insulin secretagogue or a pharmaceutical agent for the prophylaxis or treatment of diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-10-26 | — | — | US | disclosed |
| US-7820837-B2 | ethyl {6-[(3-phenoxybenzyl)oxy]-3,4-dihydronaphthalen-1-yl}acetate; having a GPR40 receptor function modulating action and being useful as an insulin secretagogue or a pharmaceutical agent for the prophylaxis or treatment of diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-10-26 | — | — | US | disclosed |