Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.79 |
| ▸ | MAPT | P10636 | 6/20 | 0.79 |
| ▸ | HTT | P42858 | 5/20 | 0.79 |
| ▸ | POLB | P06746 | 3/20 | 0.79 |
| ▸ | DDX3X | O00571 | 2/20 | 0.79 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.79 |
| ▸ | CA12 | O43570 | 2/20 | 0.73 |
| ▸ | CA1 | P00915 | 2/20 | 0.73 |
| ▸ | CA2 | P00918 | 2/20 | 0.73 |
| ▸ | CA9 | Q16790 | 2/20 | 0.73 |
| ▸ | CA5A | P35218 | 1/20 | 0.73 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.73 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | BAZ1A | Q9NRL2 | 4/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CASP3 | P42574 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL20268307 | 0.99 | MEN1 (0.77) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL1047211 | 0.89 | MEN1 (1.00) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL6129390 | 0.88 | MEN1 (0.90) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL17084065 | 0.88 | MEN1 (0.96) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL6819562 | 0.87 | KMT2A (0.72) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL29494979 | 0.85 | CNR1 (0.85) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL22092552 | 0.85 | MEN1 (0.79) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL29494985 | 0.85 | MEN1 (0.79) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL22092547 | 0.85 | MEN1 (0.79) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL22092548 | 0.85 | CNR1 (0.85) | MEN1KMT2AMAPTHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3555189-B1 | REPAIRABLE POLYMER COMPOSITIONS | KINECTRICS UK LTD (GB) | 2022-03-16 | — | — | EP | disclosed |
| US-20110275635-A1 | SMALL MOLECULE INHIBITORS OF NADS, NAMNAT, AND NMNAT | THE UAB RESEARCH FOUNDATION (US) | 2011-11-10 | — | — | US | disclosed |
| US-20110275635-A1 | SMALL MOLECULE INHIBITORS OF NADS, NAMNAT, AND NMNAT | THE UAB RESEARCH FOUNDATION (US) | 2011-11-10 | — | — | US | disclosed |
| WO-2010123591-A2 | SMALL MOLECULE INHIBITORS OF NADS, NAMNAT, AND NMNAT | THE UAB RESEARCH FOUNDATION (US) | 2010-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275635-A1 | SMALL MOLECULE INHIBITORS OF NADS, NAMNAT, AND NMNAT | NAMPT, NAPRT, NNT | MEN1 889/4885KMT2A 1419/4885MAPT 833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.